Molecular Formula | C9H20N2O2 |
Molar Mass | 188.27 |
Density | 0.984g/mLat 20°C(lit.) |
Boling Point | 292.9±23.0 °C(Predicted) |
Flash Point | 109°C |
Solubility | Chloroform, DMSO, Methanol |
Vapor Presure | 0.00179mmHg at 25°C |
Appearance | Liquid |
Color | Clear colorless to light yellow |
BRN | 1937878 |
pKa | 12.86±0.46(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | n20/D 1.460 |
MDL | MFCD00210019 |
Hazard Symbols | C - Corrosive |
Risk Codes | R34 - Causes burns R24 - Toxic in contact with skin |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
UN IDs | UN 2735 8/PG 3 |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10-34 |
HS Code | 29241990 |
Hazard Class | 8 |
Packing Group | Ⅲ |
Use | N-tert-butoxycarbonyl -1, 4-butanediamine is a mono-Boc (tert-butoxycarbonyl) protected butanediamine. Monoboc (tert-butoxycarbonyl) protected ethylenediamine, propylenediamine, butylenediamine, piperazine, homopiperazine and other compounds are important organic intermediates, which are widely used in the synthesis of dendrimers in the field of drug molecules and materials. |
preparation | 4.0g (45mmol) of 1, 4-butanediamine are dissolved in 100 of dichloromethane, the mixture was cooled in an ice bath to 0-5 ° C.; 5.8g (45mmol) of N,N-diisopropylethylamine (DIEA) was added thereto, and the mixture was stirred uniformly; after a solution of 0.9g (4.5mmol) of di-tert-butyl dicarbonate in dichloromethane was added dropwise to the above system, the reaction was continued for 12 hours; The final reaction solution was extracted 3 times with dichloromethane and washed 3 times with water, 0.7g of N-tert-butoxycarbonyl-1, 4-butanediamine (yield 80%) were obtained after drying, filtration and removal of dichloromethane by rotary evaporation. |