N-Benzyl-2-(methylthio)pyrimidin-4-amine - Names and Identifiers
N-Benzyl-2-(methylthio)pyrimidin-4-amine - Physico-chemical Properties
Molecular Formula | C12H13N3S
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Molar Mass | 231.32 |
Storage Condition | 2-8°C |
Refractive Index | 1.632 |
N-Benzyl-2-(methylthio)pyrimidin-4-amine - Risk and Safety
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
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HS Code | 29335990 |
N-Benzyl-2-(methylthio)pyrimidin-4-amine - Introduction
N-Benzyl-2-(methylthio)pyrimidin-4-amine is an organic compound with the chemical formula C13H12N4S.
Its nature mainly includes the following aspects:
1. appearance: pure product is white or white crystal powder.
2. melting point: about 180-190 degrees Celsius.
3. Solubility: high solubility in common organic solvents, such as methanol, chloroform and dimethyl sulfoxide.
This compound is commonly used as an intermediate in the pharmaceutical field and has the following uses:
1. Anti-tumor drugs: Its derivatives usually have anti-tumor activity and can be used to develop anti-cancer drugs.
2. Antibacterial drugs: The compound and its derivatives also show certain potential in antibacterial activity and can be applied to the development of antibacterial drugs.
The preparation method of the compound can be achieved by the following steps:
1. firstly, 2-methylthio -4-benzyl thiolopyrimidine reacts with benzylamine to generate N-Benzyl-2-(methylthio)pyrimidin-4-amine under the action of alkali.
2. After completion of the synthesis, the target product can be obtained by purification methods such as crystallization or column chromatography.
Some safety information needs to be noted when using and storing this compound:
1. Because the compound may produce toxic gases or vapors under certain conditions, it must be operated in a well-ventilated laboratory, wearing protective gloves, glasses and laboratory clothes.
2. Avoid contact with strong oxidants to avoid dangerous reactions.
3. Store in a dry, cool, ventilated place, avoid direct sunlight.
Please note that the information provided above is for reference only. Laboratory safety regulations and relevant regulations should be followed when handling and using this compound.
Last Update:2024-04-10 22:40:09