N-BOC-4-(Trifluoromethyl)-L-phenylalanine - Names and Identifiers
Name | BOC-L-4-Trifluoromethylphe
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Synonyms | BOC-PHE(4-CF 3)-OH BOC-L-4-Trifluoromethylphe BOC-L-4-TRIFLUOROMETHYLPHE BOC-L-PHE(4-TRIFLUOROMETHYL)-OH Boc-L-4-Trifluoromethylphenylalanine BOC-L-4-TRIFLUOROMETHYLPHENYLALANINE Boc-4-Trifluoromethyl-L-phenylalanine BOC-4-(TRIFLUOROMETHYL)-L-PHENYLALANINE N-BOC-4-(TRIFLUOROMETHYL)-L-PHENYLALANINE L-4-(TRIFLUOROMETHYL)PHENYLALANINE, BOC PROTECTED 4-(TRIFLUOROMETHYL)-L-PHENYLALANINE, BOC PROTECTED
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CAS | 114873-07-3
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InChI | InChI=1/C15H18F3NO4/c1-14(2,3)23-13(22)19-11(12(20)21)8-9-4-6-10(7-5-9)15(16,17)18/h4-7,11H,8H2,1-3H3,(H,19,22)(H,20,21)/t11-/m0/s1 |
N-BOC-4-(Trifluoromethyl)-L-phenylalanine - Physico-chemical Properties
Molecular Formula | C15H18F3NO4
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Molar Mass | 333.3 |
Density | 1.271±0.06 g/cm3(Predicted) |
Melting Point | 118-137°C |
Boling Point | 431.4±45.0 °C(Predicted) |
Flash Point | 214.7°C |
Vapor Presure | 3.29E-08mmHg at 25°C |
Appearance | powder to crystal |
Color | White to Almost white |
BRN | 5617499 |
pKa | 3.76±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.487 |
Physical and Chemical Properties | Melting point 118-137°C |
N-BOC-4-(Trifluoromethyl)-L-phenylalanine - Risk and Safety
Hazard Symbols | Xi - Irritant
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WGK Germany | 3 |
Hazard Note | Harmful/Irritant/Keep Cold |
N-BOC-4-(Trifluoromethyl)-L-phenylalanine - Introduction
BOC-L-4-Trifluoromethylphenylalanine is an organic compound with the chemical formula C11H12F3NO4.
Nature:
BOC-L-4-Trifluoromethylphenylalanine is a white crystalline solid with a distinctive odor. It is relatively stable at room temperature, soluble in some organic solvents such as dimethyl sulfoxide and methanol, and soluble in water.
Use:
BOC-L-4-Trifluoromethylphenylalanine is commonly used as a protecting group in chemical synthesis. It acts as a temporary protecting group that can be used to protect the amino function of amino acids and peptides to protect them from accidental reactions during synthesis, and then remove the protecting group when necessary.
Method:
In general, BOC-L-4-trifluoromethylphenylalanine can be prepared by introducing a protecting group (BOC) to the amino group of phenylalanine. The specific synthesis method can be adjusted and optimized according to actual needs.
Safety Information:
BOC-L-4-Trifluoromethylphenylalanine is an irritant to the skin, eyes and respiratory tract. It should be kept away from sources of fire and should wear appropriate protective equipment when used. Observe appropriate safety procedures during handling and storage and ensure proper ventilation conditions. At the same time, should also try to avoid contact with strong oxidants and acidic substances. In case of accidental contact or inhalation, rinse immediately with plenty of water and seek medical help.
Last Update:2024-04-10 22:29:15