Boc-D-Arg(Mtr)-OH is an organic compound with a chemical formula of C23H30N4O7S and a molecular weight of 490.57g/mol. The following is an introduction to its nature, use, preparation and safety information:
Nature:
Boc-D-Arg(Mtr)-OH is an amino acid derivative in the form of a white powder or a crystalline solid. It is relatively stable at room temperature, but should avoid exposure to light and humidity. It has high solubility in regular solvents (such as methanol, dimethylformamide, etc.).
Use:
Boc-D-Arg(Mtr)-OH is usually the starting material for the synthesis of polypeptides or proteins. It is a reagent for protecting amino acids and can be used for the synthesis of asymmetric synthetics and transition state analogs. In addition, it can also be used in applications such as chemical synthesis and drug cross-linking in drug research.
Method:
The preparation of Boc-D-Arg(Mtr)-OH is usually carried out by a chemical synthesis method. The specific steps include attaching a protecting group (such as a Boc protecting group) to the D-Arginine molecule, and then performing Metronidazole protection (such as an Mtr protecting group), finally, the protective group is removed by a reaction with an oxidizing agent or a reducing agent by an appropriate reaction. The specific steps and conditions of the synthesis may be adjusted as desired.
Safety Information:
Boc-D-Arg(Mtr)-OH is a relatively safe compound under normal conditions of use. However, as with any chemical compound, the following safety precautions should be taken when using it: Avoid direct contact with skin and eyes, and use chemical protective gloves and goggles. At the same time, the operation should be carried out under well-ventilated laboratory conditions, avoiding inhalation of dust or vapor from the solution. Follow proper laboratory safety practices when handling and storing this compound. In the event of an accident, flush the affected area immediately with plenty of water and seek medical attention.