N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-2-phenylacetamide
N2-Phenylacetyl guanosine
CAS: 132628-16-1
Molecular Formula: C18H19N5O6
N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-2-phenylacetamide - Names and Identifiers
| Name | N2-Phenylacetyl guanosine |
| Synonyms | N2-Phenylacetyl Gr Phenylacetylguanosine N2-Phenylacetyl guanosine N-(Phenylacetyl)guanosine N-(phenylacetyl)guanosine N2-PHENYLACETYL RIBONUCLEOSIDE GUANOSINE N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H- N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-pur N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-2-phenylacetaMide N2-Phenylacetyl guanosine N-(9-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-2-phenylacetaMide |
| CAS | 132628-16-1 |
| EINECS | 603-646-7 |
| InChI | InChI=1/C18H19N5O6/c24-7-10-13(26)14(27)17(29-10)23-8-19-12-15(23)21-18(22-16(12)28)20-11(25)6-9-4-2-1-3-5-9/h1-5,8,10,13-14,17,24,26-27H,6-7H2,(H2,20,21,22,25,28)/t10-,13-,14-,17-/m1/s1 |
N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-2-phenylacetamide - Physico-chemical Properties
| Molecular Formula | C18H19N5O6 |
| Molar Mass | 401.37 |
| Density | 1.73 |
| Melting Point | 189℃ |
| pKa | 8.80±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.784 |
N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-2-phenylacetamide - Introduction
N2-Phenylacetylguanosine, also known as N2-(2-phenylacetyl) guanosine (N2-(2-phenyl) adenosine), is a compound formed by linking the nucleoside moiety of guanosine to a 2-phenylacetyl group.
The properties and uses of this compound are as follows:
-Properties: N2-Phenylacetylguanine nucleoside is a white crystalline solid, stable at room temperature. It can be dissolved in solvents such as water, methanol and chloroform. The phenylacetyl group in its chemical structure brings a certain lipophilic nature.
-Purpose: N2-phenylacetylguanine nucleoside is often used as a reagent in biochemical and medicinal chemistry research. It can be used as an intermediate in the synthesis of new drugs and participate in drug development and synthesis. In addition, it is used as an indicator reagent and substrate in biochemical experiments.
The preparation of N2-phenylacetylguanine nucleoside is generally achieved by chemical synthesis. A common synthetic method is to prepare the target product by reacting 2-phenylacetyl chloride or 2-phenylacetyl acid with guanosine.
Regarding safety information, the toxicity and safety information of N2-phenylacetylguanosine has not been reported in detail, so it needs to be handled with caution when using it. Follow laboratory safety practices and wear appropriate protective equipment, such as gloves and safety glasses. At the same time, ensure that the experiment is carried out in a safe and ventilated environment and avoid inhaling vapors or solutions. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help. Exact safety information requires reference to the chemical's Safety Data Sheet (MSDS).
The properties and uses of this compound are as follows:
-Properties: N2-Phenylacetylguanine nucleoside is a white crystalline solid, stable at room temperature. It can be dissolved in solvents such as water, methanol and chloroform. The phenylacetyl group in its chemical structure brings a certain lipophilic nature.
-Purpose: N2-phenylacetylguanine nucleoside is often used as a reagent in biochemical and medicinal chemistry research. It can be used as an intermediate in the synthesis of new drugs and participate in drug development and synthesis. In addition, it is used as an indicator reagent and substrate in biochemical experiments.
The preparation of N2-phenylacetylguanine nucleoside is generally achieved by chemical synthesis. A common synthetic method is to prepare the target product by reacting 2-phenylacetyl chloride or 2-phenylacetyl acid with guanosine.
Regarding safety information, the toxicity and safety information of N2-phenylacetylguanosine has not been reported in detail, so it needs to be handled with caution when using it. Follow laboratory safety practices and wear appropriate protective equipment, such as gloves and safety glasses. At the same time, ensure that the experiment is carried out in a safe and ventilated environment and avoid inhaling vapors or solutions. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help. Exact safety information requires reference to the chemical's Safety Data Sheet (MSDS).
Last Update：2024-04-09 21:11:58
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N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-2-phenylacetamide
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1853230-29-1
398996-29-7