N-(6-chloropyridin-2-yl)pivalamide - Names and Identifiers
Name | N-(6-chloropyridin-2-yl)-2,2-dimethylpropanamide
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Synonyms | N-(6-chloropyridin-2-yl)pivalamide N-(6-chloropyridin-2-yl)-2,2-dimethylpropanamide N-(6-chloro-2-pyridinyl)-2,2-dimethylpropanamide Propanamide, N-(6-chloro-2-pyridinyl)-2,2-dimethyl- N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE
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CAS | 86847-84-9
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EINECS | 604-604-1 |
InChI | InChI=1/C10H13ClN2O/c1-10(2,3)9(14)13-8-6-4-5-7(11)12-8/h4-6H,1-3H3,(H,12,13,14) |
N-(6-chloropyridin-2-yl)pivalamide - Physico-chemical Properties
Molecular Formula | C10H13ClN2O
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Molar Mass | 212.68 |
Density | 1.199±0.06 g/cm3(Predicted) |
Melting Point | 86-87 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3)) |
Boling Point | 375.4±27.0 °C(Predicted) |
Flash Point | 180.826°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 13.15±0.70(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.561 |
N-(6-chloropyridin-2-yl)pivalamide - Risk and Safety
Risk Codes | 22 - Harmful if swallowed
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Hazard Class | IRRITANT |
N-(6-chloropyridin-2-yl)pivalamide - Introduction
N-(6-chloropyridin-2-yl)-2,2-dimethylpropylamide (N-(6-chloropyridin-2-yl)-2,2-dimethylpropylamide) is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow solid
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and dichloromethane (DCM)
-Molecular formula: C12H15ClN2O
-Molecular weight: 238.71g/mol
Use:
N-(6-chloropyridin-2-yl)-2,2-dimethylpropanamide is an important organic synthesis intermediate with a wide range of applications. It is often used in the preparation of pesticides, pharmaceuticals and other organic substances. It can be used as an active ingredient in the pharmaceutical field, or as a catalyst or reagent in organic synthesis reactions.
Preparation Method:
The preparation method of N-(6-chloropyridin-2-yl)-2,2-dimethylpropanamide can be obtained by the hydroxyformylation of pyridine and the chlorination of teropentyl. The specific steps include first reacting pyridine with formic acid to form pyridine-2-carboxylic acid, and then reacting with a terpentyl chlorinating agent to form a product.
Safety Information:
- N-(6-chloropyrin-2-yl)-2,2-dimethylpropanamide is an organic compound and requires safe operation methods in a laboratory or industrial environment.
-Wear appropriate personal protective equipment such as laboratory gloves, glasses and protective clothing when using the compound.
-Avoid direct contact with the skin, avoid inhaling its vapor or dust.
-Pay attention to fire prevention and ventilation during operation to ensure the stability and safety of the operating environment.
-Keep dry and sealed during storage, and avoid contact with harmful substances such as oxidants, acids and high temperatures.
Last Update:2024-04-09 02:00:48