N-(2-phenylethyl)acetamide
N-(2-phenylethyl)acetamide
CAS: 877-95-2
Molecular Formula: C10H13NO
N-(2-phenylethyl)acetamide - Names and Identifiers
| Name | N-(2-phenylethyl)acetamide |
| Synonyms | Glipizide Impurity 1 Glipizide Impurity 15 N-phenethylacetramide (2-Phenethyl)acetamide N-Acetylphenethylamine N-(2-phenylethyl)acetamide n-(2-phenylethyl)-acetamid N-(2-Phenylethyl)-acetamide n-beta-phenylethylacetamide Acetamide, N-(2-phenylethyl)- |
| CAS | 877-95-2 |
| EINECS | 212-897-8 |
| InChI | InChI=1/C10H13NO/c1-9(12)11-8-7-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,11,12) |
| InChIKey | MODKMHXGCGKTLE-UHFFFAOYSA-N |
N-(2-phenylethyl)acetamide - Physico-chemical Properties
| Molecular Formula | C10H13NO |
| Molar Mass | 163.22 |
| Density | 1.012 |
| Melting Point | 48-52 °C |
| Boling Point | 154 °C / 2mmHg |
| Flash Point | 204°C |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Vapor Presure | 5.69E-05mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 16.17±0.46(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.5400 (estimate) |
| MDL | MFCD00026177 |
N-(2-phenylethyl)acetamide - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| RTECS | AC7740000 |
| HS Code | 29241900 |
N-(2-phenylethyl)acetamide - Introduction
N-(2-phenylethyl)acetamide(N-(2-phenylethyl)acetamide) is an organic compound with the following properties and uses:
Nature:
-Appearance: Colorless to light yellow crystal
-Molecular formula: C10H13NO
-Molecular weight: 163.22g/mol
-Melting Point: 58-62°C
-Boiling point: 294°C
-Solubility: Soluble in polar solvents such as ethanol, chloroform and dimethyl sulfoxide
Use:
-Pharmaceutical field: N-(2-phenylethyl)acetamide are often used as intermediates for the synthesis of drugs and bioactive molecules. It is used as a raw material for anticancer drugs, bioactive agents and transdermal drug delivery agents.
Preparation Method:
The preparation method of N-(2-phenylethyl)acetamide can be achieved in a variety of ways, one of which is a common method through the following steps:
1. take acetophenone as a starting material and react with bromoacetic acid to form N-bromoacyl -2-phenylethylamine.
2. Next, N-bromoacyl-2-phenylethylamine is reacted with ammonia to produce N-(2-phenylethyl)acetamide.
3. Finally, the target product is obtained by crystallization or other purification methods.
Safety Information:
N-(2-phenylethyl)acetamide related safety information lack of clear reporting and evaluation. However, as a general guideline when handling chemicals, the following safety precautions should be observed when using:
-Avoid contact with skin, eyes and taking. In case of contact, rinse immediately with plenty of water.
-Appropriate protective measures, such as laboratory gloves and safety glasses, should be used during operation.
-When used in a laboratory environment, follow appropriate safety practices and laboratory regulations.
-Before use, you should carefully read and understand the relevant material safety data sheets (MSDS) that affect health and safety.
Nature:
-Appearance: Colorless to light yellow crystal
-Molecular formula: C10H13NO
-Molecular weight: 163.22g/mol
-Melting Point: 58-62°C
-Boiling point: 294°C
-Solubility: Soluble in polar solvents such as ethanol, chloroform and dimethyl sulfoxide
Use:
-Pharmaceutical field: N-(2-phenylethyl)acetamide are often used as intermediates for the synthesis of drugs and bioactive molecules. It is used as a raw material for anticancer drugs, bioactive agents and transdermal drug delivery agents.
Preparation Method:
The preparation method of N-(2-phenylethyl)acetamide can be achieved in a variety of ways, one of which is a common method through the following steps:
1. take acetophenone as a starting material and react with bromoacetic acid to form N-bromoacyl -2-phenylethylamine.
2. Next, N-bromoacyl-2-phenylethylamine is reacted with ammonia to produce N-(2-phenylethyl)acetamide.
3. Finally, the target product is obtained by crystallization or other purification methods.
Safety Information:
N-(2-phenylethyl)acetamide related safety information lack of clear reporting and evaluation. However, as a general guideline when handling chemicals, the following safety precautions should be observed when using:
-Avoid contact with skin, eyes and taking. In case of contact, rinse immediately with plenty of water.
-Appropriate protective measures, such as laboratory gloves and safety glasses, should be used during operation.
-When used in a laboratory environment, follow appropriate safety practices and laboratory regulations.
-Before use, you should carefully read and understand the relevant material safety data sheets (MSDS) that affect health and safety.
Last Update：2024-04-09 21:00:56
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Product Name: N-(2-Phenylethyl)-acetamide Visit Supplier Webpage Request for quotationCAS: 877-95-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
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Product Name: N-(2-Phenylethyl)acetamide Visit Supplier Webpage Request for quotationCAS: 877-95-2
Tel: +86-18821248368
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Mobile: +86-18821248368
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WhatsApp: +86-18821248368
Product Name: N-(2-Phenethyl)Acetamide Visit Supplier Webpage Request for quotation
CAS: 877-95-2
Tel: 18301782025
Email: 3008007409@qq.com
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QQ: 3008007409
CAS: 877-95-2
Tel: 18301782025
Email: 3008007409@qq.com
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View History
N-(2-phenylethyl)acetamide
4-硝基苯-D-吡喃半乳苷糖
BENZYL 4-(2-AMINOPROPYL)PIPERAZINE-1-CARBOXYLATE
4'-Demethyldehydropodophyllotoxin
5-氟喹啉-8-胺(盐酸盐)
methyl 2,6,6-trimethylcyclohex-3-ene-1-carboxylate
6-氟-3-甲基-1H-吲唑
4-溴-6,7-二氢-5H-吡咯并[3,4-B]吡啶
D(+)-A-HYDRAZINOHISTIDINE HYDROCHLORIDE
ACETYL HYDROXYPROLINE
4-硝基苯-D-吡喃半乳苷糖
BENZYL 4-(2-AMINOPROPYL)PIPERAZINE-1-CARBOXYLATE
4'-Demethyldehydropodophyllotoxin
5-氟喹啉-8-胺(盐酸盐)
methyl 2,6,6-trimethylcyclohex-3-ene-1-carboxylate
6-氟-3-甲基-1H-吲唑
4-溴-6,7-二氢-5H-吡咯并[3,4-B]吡啶
D(+)-A-HYDRAZINOHISTIDINE HYDROCHLORIDE
ACETYL HYDROXYPROLINE