N,N-diethyl-2-hydroxyacetamide - Names and Identifiers
N,N-diethyl-2-hydroxyacetamide - Physico-chemical Properties
Molecular Formula | C6H13NO2
|
Molar Mass | 131.17 |
Density | 1.009 g/mL at 25 °C (lit.) |
Boling Point | 238 °C (lit.) |
Flash Point | 220°F |
Solubility | Chloroform (Sparingly), Methanol (Slightly) |
Vapor Presure | 0.0216mmHg at 25°C |
Appearance | Oil |
Color | Colourless |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | n20/D 1.457(lit.) |
N,N-diethyl-2-hydroxyacetamide - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
WGK Germany | 3 |
N,N-diethyl-2-hydroxyacetamide - Introduction
N,N-diethyl-2-hydroxyacetamide is an organic compound with the chemical formula C8H17NO2.
Nature:
1. Appearance: colorless to yellowish liquid.
2. Solubility: Soluble in water and most organic solvents.
3. melting point: about 23-26 ℃.
4. Boiling point: about 220-225 ℃.
5. Density: about 0.979g/cm3.
6. chemical properties: as amide compounds, with acid-base neutralization ability.
Use:
1. As an additive in cosmetics and personal care products, such as moisturizer, shampoo, etc., it has the effect of moisturizing and softening the skin.
2. as pharmaceutical intermediates, commonly used in the synthesis of compounds with anti-cancer, anti-virus, anti-infection and other biological activities.
3. Used as a chemical in the agricultural field, it can be used to prepare pesticides and insecticides.
Preparation Method:
N,N-diethyl-2-hydroxyacetamide can be synthesized by the following steps:
1. Reaction of diethyl acetamide with sodium hydroxide, hydrolysis reaction in ethanol to give N,N-diethyl-2-hydroxyacetamide.
2. Filtration to obtain the product.
Safety Information:
1. N,N-diethyl-2-hydroxyacetamide has a stimulating effect on the skin and eyes, and should avoid contact when using or operating.
2. need to operate in a well-ventilated place, avoid inhaling its steam.
3. if the external contact to the skin or eyes, immediately rinse with plenty of water, and seek medical advice.
4. need to be stored in a cool, dry, ventilated place, away from fire and oxidant.
5. When using the compound, you should follow the relevant safety procedures, wear personal protective equipment, and avoid inhalation or intake.
Last Update:2024-04-09 02:00:45