Molecular Formula | C11H12O3 |
Molar Mass | 192.21 |
Density | d2020 1.1437 |
Melting Point | -20℃ |
Boling Point | bp40 173° |
Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
Appearance | Morphological oil |
Color | clear, light yellow |
BRN | 166218 |
Storage Condition | 2-8°C |
Refractive Index | nD20 1.54032 |
MDL | MFCD00133549 |
Physical and Chemical Properties | Chemical properties yellow oily liquid, soluble in methanol, ethanol, DMSO and other organic solvents, derived from nutmeg Myristica fragrans Houtt. Sheath Shanxiong, medicinal Peucedanum leaf. |
Use | Uses myristicether has anti-tumor, antifungal, larvicidal activity and inhibition of liver lipid peroxidation. |
Risk Codes | 52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
Safety Description | 61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
UN IDs | UN 3082 9/PG 3 |
WGK Germany | 1 |
RTECS | CY2625000 |
FLUKA BRAND F CODES | 10-23 |
Toxicity | A naturally occurring methylenedioxyphenyl compound found in nutmeg. It has been suggested that myristicin may be responsible, in whole or in part, for the toxicity of nutmeg. The spice (5-15 g) causes symptoms similar to atropine poisoning: flushing of the skin, tachycardia, absence of salivation, and excitation of the CNS. Euphoria and hallucinations have given rise to abuse of this material. As a methylenedioxyphenyl compound, myristicin gives rise to a type III spectrum with reduced cytochrome P450 and can inhibit monooxygenations catalyzed by this cytochrome. |
Reference Show more | 1. Lin Lin Yu Feng Rui Xu Lihua et al. Determination of seven volatile components in nujin pills by GC [J]. Chinese Journal of Experimental prescriptions 2018 024(024):73-77. 2. [IF = 6.684] Zhang Jili et al."Licarin-B." Front Cell Dev Biol. 2021 Jun;0:1499 |
toxic substance data | 607-91-0(Hazardous Substances Data) |
biological activity
Myristicin (Myristicine) is a terpene-like active ingredient in the Myristica fragrans seed Nutmeg. It is a weak inhibitor of monamine oxidase (MAO) and a mechanistic inhibitor of CYP1A2.
Target
Target Value
MAO
CYP1A2
category
Pesticides
Toxicity classification
Poisoning
Acute toxicity
oral-rat LD50: 4620 mg/kg
storage and transportation features
The warehouse is ventilated and dry at low temperature; stored and transported separately from food ingredients
Fire extinguishing agent
Dry powder, foam, sand
NIST chemical information | 1,3-Benzodioxole, 4-methoxy-6-(2-propenyl)-(607-91-0) |