Molecular Formula | C9H13Cl2N5O |
Molar Mass | 278.14 |
Density | 1.52 g/cm3 |
Melting Point | 189° |
Boling Point | 364.7 °C at 760 mmHg |
Flash Point | 174.3 °C |
Water Solubility | Soluble to 100 mM in DMSO or to 100 mM in ethanol |
Solubility | 10 mM in DMSO |
Storage Condition | -20℃ |
Physical and Chemical Properties | Appearance:White solid |
Use | Used as a blood pressure lowering drug |
WGK Germany | 3 |
RTECS | UV6260290 |
crystallized from isopropanol monoethyl ether, melting point 189 °c.
5-amino -4,6-= chloro-2-methylpyrimidine and 1-acetyl -2-flavor oxazoline -2-one reaction, the resulting product and sodium methoxide acted on moxonidine. Or by 5-amino -4-chlorine -6-methoxy -2-methyl pyrimidine and ammonium thiocyanate and benzoyl chloride reaction, the resulting compound by benzoyl, methylation of the resulting product again and ethylenediamine to the role of moxonidine.
developed by Beiersdorf, Inc., Germany, was launched in 1991. As a second-generation central antihypertensive drug, its hypotensive effect is similar to that of the calcium antagonist nifedipine and the ACE inhibitor captopril. For essential hypertension.