Name | Moxonidine |
Synonyms | be5895 bdf5895 BDF-5895 MOXONIDINE Moxonidine BDF-5895 HCL MOXONIDINE HCL 4-Chloro-6-Methoxy-2-Methyl-5-(2-Imidazolin-2-YL)Aminopyrimidine 4-CHLORO-6-METHOXY-2-METHYL-5-(2-IMIDAZOLIN-2-YL)AMINOPYRIMIDINE HCL 4-chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamin 4-Chloro-N-(4,5-Dihydro-1H-Imidazol-2-YL)-6-Methoxy-2-Methyl-5-Pyrimidinamine 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine 4-CHLORO-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-6-METHOXY-2-METHYL-5-PYRIMIDINAMINE HYDROCHLORIDE |
CAS | 75438-57-2 |
EINECS | 629-833-3 |
InChI | InChI=1/C9H12ClN5O/c1-5-13-7(10)6(8(14-5)16-2)15-9-11-3-4-12-9/h3-4H2,1-2H3,(H2,11,12,15) |
InChIKey | WPNJAUFVNXKLIM-UHFFFAOYSA-N |
Molecular Formula | C9H12ClN5O |
Molar Mass | 241.68 |
Density | 1.52±0.1 g/cm3(Predicted) |
Melting Point | 217-219° (dec) |
Boling Point | 364.7±52.0 °C(Predicted) |
Flash Point | 174.3°C |
Water Solubility | 800.3mg/L(temperature not stated) |
Solubility | Very slightly soluble in water, sparingly soluble in methanol, slightly soluble in methylene chloride, very slightly soluble in acetonitrile. |
Vapor Presure | 1.66E-05mmHg at 25°C |
Appearance | neat |
Color | White to Almost white |
Merck | 14,6293 |
pKa | 7.11±0.10(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.68 |
Physical and Chemical Properties | Crystallization, melting point 217-219 C (decomposition). Moxonidine Hydrochloride: C9H12ClN5O? xHCl. [75438-58-3]. Crystallization from isopropanol-diethyl ether, melting point 189 °c. |
Use | It acts by stimulating central presynaptic alpha 2-receptors. The hypotensive effect was similar to that of the calcium antagonist nifedipine and the ACE inhibitor captopril. For essential hypertension. |
UN IDs | UN 2811 6.1/PG III |
WGK Germany | 3 |
RTECS | UV6260290 |
Hazard Class | 6.1 |
Packing Group | III |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 4.138 ml | 20.689 ml | 41.377 ml |
5 mM | 0.828 ml | 4.138 ml | 8.275 ml |
10 mM | 0.414 ml | 2.069 ml | 4.138 ml |
5 mM | 0.083 ml | 0.414 ml | 0.828 ml |