Mebeverinum
MEBEVERINE
CAS: 3625-06-7
Molecular Formula: C25H35NO5
Mebeverinum - Names and Identifiers
Mebeverinum - Physico-chemical Properties
| Molecular Formula | C25H35NO5 |
| Molar Mass | 429.55 |
| Density | 1.074±0.06 g/cm3(Predicted) |
| Melting Point | 129-131 °C |
| Boling Point | 543.8±50.0 °C(Predicted) |
| pKa | 9.51±0.50(Predicted) |
| Storage Condition | 2-8°C |
Mebeverinum - Reference Information
| antispasmodic agent | Mebeverine is a myophilic antispasmodic agent that acts directly on the smooth muscles of the gastrointestinal tract to relieve spasticity, at the same time does not affect the normal intestinal movement. These nerves Impulse cause spasms when the intestine is stimulated for any reason, and mebeverine blocks the nerves Impulse of the brain by replacing acetylcholine. The researchers believe that Mebeverine can also inhibit calcium channel supplementation, by interfering with the movement of calcium ions, can slow muscle contraction. Unlike other antispasmodic drugs, Mebeverine has the characteristic that site-specific drugs do not compete with receptors throughout the body, but especially those that are only attached to the intestine, patients taking Mebeverine do not experience any side effects associated with other antispasmodic or anticholinergic drugs, nor do Mebeverine usually affect the cardiovascular or central nervous system. The original research was approved for marketing in China in 2016. In 2018, the market sales of anticholinergic drugs and synthetic antispasmodic preparations in China exceeded 2 billion yuan. The market is far from meeting the health consumption demand of people suffering from digestive system diseases and residents in China, the market of anticholinergic and synthetic antispasmodic preparations in China will be further expanded. |
| indication | symptomatic treatment of Abdominal Pain spasticity, bowel dysfunction and bowel discomfort caused by irritable bowel syndrome, treatment of intestinal spasms secondary to organic disease. |
| side effects | Head Pain, dizziness, abdominal distension, Nausea, skin allergy, etc. It is contraindicated in those who are allergic to mebeverine hydrochloride, those who are contraindicated in patients with intestinal obstruction, those with fecal impaction and colonic relaxation, and those with severe hepatic insufficiency. Should be taken 20min before meals, and should be swallowed, do not chew. |
Last Update：2024-04-10 22:29:15
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Product Name: MEBEVERINE Visit Supplier Webpage Request for quotation
CAS: 3625-06-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 3625-06-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
Mebeverinum
1,3,2-Dioxaborolane, 2-[2-(difluoromethyl)-4-fluorophenyl]-4,4,5,5-tetramethyl-
1-[3,5-BIS(TRIFLUOROMETHYL)BENZYL]-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBOXYLIC ACID
N-(9-{(1R,3R,4R,7S)-1-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-7-hydroxy-2,5-dioxa-bicyclo[2.2.1]hept-3-yl}-6-oxo-6,9-dihydro-1H-purin-2-yl)-isobutyramide
3-(TRIFLUOROMETHYL)-N-(2,2-DIMETHOXYETHYL)-1H-PYRAZOLE-5-CARBOXAMIDE
2-Piperidineacetimidic acid, hydrazide (8CI)
6-(4-FLUOROPHENYL)-2-[(3,4,4-TRIFLUORO-3-BUTENYL)SULFANYL][1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YLAMINE
2,5-Methano-2H-indeno[1,2-b]oxirene, 2,3,4,5,6,7,7-heptachloro-1a,1b,5,5a,6,6a-hexahydro-, (1aalpha,1bbeta,2alpha,5alpha,5abeta,6beta,6aalpha)-
rac 2-[3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-methyl-phenol-d14 Hydrochloride
6-Chloro-3-cyano-7-azaindole
1,3,2-Dioxaborolane, 2-[2-(difluoromethyl)-4-fluorophenyl]-4,4,5,5-tetramethyl-
1-[3,5-BIS(TRIFLUOROMETHYL)BENZYL]-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBOXYLIC ACID
N-(9-{(1R,3R,4R,7S)-1-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-7-hydroxy-2,5-dioxa-bicyclo[2.2.1]hept-3-yl}-6-oxo-6,9-dihydro-1H-purin-2-yl)-isobutyramide
3-(TRIFLUOROMETHYL)-N-(2,2-DIMETHOXYETHYL)-1H-PYRAZOLE-5-CARBOXAMIDE
2-Piperidineacetimidic acid, hydrazide (8CI)
6-(4-FLUOROPHENYL)-2-[(3,4,4-TRIFLUORO-3-BUTENYL)SULFANYL][1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YLAMINE
2,5-Methano-2H-indeno[1,2-b]oxirene, 2,3,4,5,6,7,7-heptachloro-1a,1b,5,5a,6,6a-hexahydro-, (1aalpha,1bbeta,2alpha,5alpha,5abeta,6beta,6aalpha)-
rac 2-[3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-methyl-phenol-d14 Hydrochloride
6-Chloro-3-cyano-7-azaindole