Molecular Formula | C22H26FN3O2 |
Molar Mass | 383.46 |
Density | 1.20±0.1 g/cm3(Predicted) |
Boling Point | 529.4±50.0 °C(Predicted) |
pKa | 7.75±0.46(Predicted) |
Storage Condition | 2-8℃ |
In vivo study | In spontaneously hypertensive stroke-prone rats (SHR-SP), Losmapimod significantly improves survival, endothelial cell-dependent and independent vasodilation, and renal function indices, and subsequently attenuates dyslipidemia, hypertension, and cardiac remodeling, plasma renin activity (PRA), aldosterone, and interleukin-1β (IL-1β). |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.608 ml | 13.039 ml | 26.078 ml |
5 mM | 0.522 ml | 2.608 ml | 5.216 ml |
10 mM | 0.261 ml | 1.304 ml | 2.608 ml |
5 mM | 0.052 ml | 0.261 ml | 0.522 ml |