Lorestat
TOLRESTAT
CAS: 82964-04-3
Molecular Formula: C16H14F3NO3S
Lorestat - Names and Identifiers
Lorestat - Physico-chemical Properties
| Molecular Formula | C16H14F3NO3S |
| Molar Mass | 357.35 |
| Density | 1.399±0.06 g/cm3(Predicted) |
| Melting Point | 164-165° |
| Boling Point | 498.1±55.0 °C(Predicted) |
| Solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly) |
| Appearance | powder |
| Color | white to beige |
| pKa | 3.49±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Physical and Chemical Properties | Crystallization, melting point 164-165 ℃. Tolrestat Methyl Ester: C17H16F3NO3S. Melting point 109~110 ℃. |
| In vivo study | Tolrestat (1.8 mg/kg per day) causes a reversal to normal RBC sorbitol levels diabetic rats. In 21-day diabetic rats, the estimated ID in the sciatic nerve and lenses is 4.8 and about 20 for tolrestat, and 1.7 and 2.2 for (±)sorbinil,respectively. Either tolrestat or sorbinil inhibits tissue AR activity but does not significantly affect plasma lipoprotein levels, or affect the body weight of the mice or their general health. Accumulation of cholesterol-rich foam cells is significantly increased in aortic roots of tolrestat-fed mice. |
Lorestat - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.798 ml | 13.992 ml | 27.984 ml |
| 5 mM | 0.56 ml | 2.798 ml | 5.597 ml |
| 10 mM | 0.28 ml | 1.399 ml | 2.798 ml |
| 5 mM | 0.056 ml | 0.28 ml | 0.56 ml |
Last Update：2024-01-02 23:10:35
Supplier List
Multiple SpecificationsSpot supply
Product Name: AY-27773 Visit Supplier Webpage Request for quotationCAS: 82964-04-3
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: TOLRESTAT Visit Supplier Webpage Request for quotationCAS: 82964-04-3
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: TOLRESTAT Visit Supplier Webpage Request for quotationCAS: 82964-04-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Tolrestat Visit Supplier Webpage Request for quotationCAS: 82964-04-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: TOLRESTAT Visit Supplier Webpage Request for quotation
CAS: 82964-04-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 82964-04-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Multiple SpecificationsSpot supply
Product Name: AY-27773 Visit Supplier Webpage Request for quotationCAS: 82964-04-3
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: TOLRESTAT Visit Supplier Webpage Request for quotationCAS: 82964-04-3
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: TOLRESTAT Visit Supplier Webpage Request for quotationCAS: 82964-04-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Tolrestat Visit Supplier Webpage Request for quotationCAS: 82964-04-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: TOLRESTAT Visit Supplier Webpage Request for quotation
CAS: 82964-04-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 82964-04-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
Lorestat
化合物D-LIN-MC3-DMA
2-(4-氨基苯基)丙烷-2-醇
1-Deoxy-1-[[2-[(ethoxycarbonyl)aMino]-5-[[(4-fluorophenyl)Methyl]aMino]pheny-d4l]aMino] β-D-Glucopyranuronic Acid
依达拉奉P3
c anhydride and rosin
124499-27-0
D-glucitol 1,1',1''-[3,3',3''-[(methylstannylidyne)tris(thio)]tris[propionate]]
12-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)DODECANOIC ACID
1-[2-(2,5-二甲基-1H-吡咯-1-基)乙基]哌啶
化合物D-LIN-MC3-DMA
2-(4-氨基苯基)丙烷-2-醇
1-Deoxy-1-[[2-[(ethoxycarbonyl)aMino]-5-[[(4-fluorophenyl)Methyl]aMino]pheny-d4l]aMino] β-D-Glucopyranuronic Acid
依达拉奉P3
c anhydride and rosin
124499-27-0
D-glucitol 1,1',1''-[3,3',3''-[(methylstannylidyne)tris(thio)]tris[propionate]]
12-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)DODECANOIC ACID
1-[2-(2,5-二甲基-1H-吡咯-1-基)乙基]哌啶