LYPRESSIN
lypressin
CAS: 50-57-7
Molecular Formula: C46H65N13O12S2
LYPRESSIN - Names and Identifiers
LYPRESSIN - Physico-chemical Properties
| Molecular Formula | C46H65N13O12S2 |
| Molar Mass | 1056.22 |
| Density | 1.1080 (rough estimate) |
| Boling Point | 1610.4°C at 760 mmHg |
| Flash Point | 927.7°C |
| Vapor Presure | 0mmHg at 25°C |
| Storage Condition | -20°C |
| Refractive Index | 1.6700 (estimate) |
| Use | Treatment of diabetes insipidus |
LYPRESSIN - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 20 - Harmful by inhalation |
| Safety Description | 36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | YW8659000 |
| HS Code | 2937190000 |
LYPRESSIN - Nature
Open Data Verified Data
This product is a synthetic, colorless and transparent solution of levopressin, pH 3.7~4.3, containing buffer sodium acetate, antibacterial agent trichloromethyl tert-butyl alcohol and sodium chloride. It has various biological activities of natural vasopressin, and the antidiuretic effect of each unit of vasopressin is equivalent to human "fine pressure
The vasoconstrictive properties of "one-half" are only apparent when high doses are administered. The action time is shorter than that of diabetes insipidus, only about 4 hours.
Last Update：2024-01-02 23:10:35
LYPRESSIN - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 0.947 ml | 4.734 ml | 9.468 ml |
| 5 mM | 0.189 ml | 0.947 ml | 1.894 ml |
| 10 mM | 0.095 ml | 0.473 ml | 0.947 ml |
| 5 mM | 0.019 ml | 0.095 ml | 0.189 ml |
Last Update：2024-01-02 23:10:35
LYPRESSIN - Use
Open Data Verified Data
- applicable to moderate and mild pituitary diabetes insipidus.
- usage and dosage of each spray to the nasal cavity one or two, 3 to 5 times a day. The nasal mucosa stimulation was lighter than that of diabetes insipidus powder.
- formulation 5mL/vial (50 vasopressin units per mL).
Last Update：2022-01-01 11:11:34
LYPRESSIN - Safety
Open Data Verified Data
The allergic reaction was smaller than that of vasopressin extracted from animals because of the Nonspecific protein. Common ulcerative epistaxis. Patients with coronary artery aneurysm and epilepsy.
Last Update：2022-01-01 11:11:34
LYPRESSIN - Reference Information
| use | vasopressin's main physiological function is to regulate extracellular fluid volume, promote renal tubular reabsorption of water, constrict blood vessels and cause increased blood pressure. Insufficient secretion of vasopressin causes symptoms such as polyuria, dehydration, and thirst. Lysine vasopressin (lysine acetate) is a synthetic derivative of vasopressin. Its antidiuretic and vasoconstriction effects are relatively gentle, and it can be used as an intermediate in pharmaceutical synthesis. |
| application | the drugs used in clinical research to directly stimulate corticotropin are mainly arginine vasopressin, alanine vasopressin and sheep and human corticotropin releasing hormone, but arginine vasopressin and lysine vasopressin (lysine acetate) are commonly used, although diarginine vasopressin is called lysine vasopressin (lysine acetate) has a strong effect and good tolerance, it often fails to reach the exciting state of new communication in the insulin test. The test results show that the joint test of corticotropin releasing hormone and lysine vasopressin (lysine acetate) in sheep and humans can effectively and safely evaluate the reserve function of the pituitary gland, and the repeatability is good, but it should be used with caution in elderly and hypertensive patients. |
| biological activity | Lysipressin is an antidiuretic hormone found in pigs, which can induce the contraction of rabbit bladder smooth muscle and activate adenylate cyclase. |
Last Update：2024-04-09 19:05:03
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tech@medchemexpress.com
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CAS: 50-57-7
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CAS: 50-57-7
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