Molecular Formula | C23H24ClN5O |
Molar Mass | 421.92 |
Density | 1.37±0.1 g/cm3(Predicted) |
Boling Point | 709.7±60.0 °C(Predicted) |
Solubility | DMSO: ≥ 50 mg/mL |
pKa | 15.81±0.20(Predicted) |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.37 ml | 11.851 ml | 23.701 ml |
5 mM | 0.474 ml | 2.37 ml | 4.74 ml |
10 mM | 0.237 ml | 1.185 ml | 2.37 ml |
5 mM | 0.047 ml | 0.237 ml | 0.474 ml |
biological activity | CCT251545 is a potent, the IC50 value in 7dF3 cells was 5 nM. CCT251545 can also be used as a selective chemical probe to investigate the role of CDK8 and CDK19 in human diseases. |
Target | Value |
CDK8 () | |
CDK19 () | |
Wnt (in 7dF3 cells) | 5 nM |