Name | L-hydroorotic acid |
Synonyms | L-HYDROOROTIC ACID L-hydroorotic acid L-DIHYDROOROTIC ACID L-Dihydroorotic acid DIHYDRO-L-OROTIC ACID (S)-(+)-HYDROOROTIC ACID (4S)-2,6-dioxo-1,3-diazinane-4-carboxylic acid 2,6-Dioxohexahydro-4-pyrimidinecarboxylic acid (S)-2,6-Dioxohexahydro-4-pyrimidinecarboxylic acid L-4,5-Dihydroorotic acid~(S)-(+)-2,6-Dioxohexahydro-4-pyrimidinecarboxylic acid |
CAS | 5988-19-2 |
EINECS | 624-952-7 |
InChI | InChI=1/C5H6N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h2H,1H2,(H,9,10)(H2,6,7,8,11)/t2-/m0/s1 |
InChIKey | UFIVEPVSAGBUSI-REOHCLBHSA-N |
Molecular Formula | C5H6N2O4 |
Molar Mass | 158.11 |
Density | 1.523 |
Melting Point | 254-255°C (dec.)(lit.) |
Boling Point | 283.16°C (rough estimate) |
Water Solubility | Soluble in water (partly), and dimethyl formamide. |
Solubility | DMSO (Slightly), Water (Slightly, Heated, Sonicated) |
Appearance | Powder |
Color | White to off-white |
pKa | 2.82±0.20(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.5090 (estimate) |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
Reference Show more | 1. Analysis of taste components of yeast extract and the effect of compound seasoning on the flavor of silver carp. |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
trait | nucleotides are white crystalline powders. |
physiological function | nucleotides (NTs) are a class of small molecules with important biological functions, it is a biological macromolecule nucleic acid (NA), that is, the precursor of DNA and RNA, which participates in almost all biochemical reactions in the body. The organism can either undergo de novo synthesis or salvage synthesis using intracellular metabolites. NTs is also a common component of the human diet, which can be absorbed and incorporated into the body's tissues. Because dietary NTs and nucleic acid have basically the same metabolic pathways in digestion, absorption and metabolism in the body, and their biological effects are also very similar, it is reasonable to speculate that whether oral NTs or nucleic acid, the nutritional effects they exert in the body are similar. |
apply | flavor enhancer. As a seasoning: guanosine (GMP), inosinic acid (IMP) and other nucleotides belong to the taste of nucleotides, in addition to its own umami, and L-glutamic acid (msg) combination, it has the function of improving the flavor, and is used as the raw material of seasoning and soup. As a food additive: Breast milk contains uridine acid (UMP), cytidine acid (CMP), adenosine monophosphate (AMP), guanosine monophosphate (GMP), inosine monophosphate (IMP) and other nucleotides, in order to improve the immune regulation function and memory of infants, the infant milk powder produced in Europe, America, Japan and other countries is added with trace nucleotides according to the content of breast milk. There are also examples of the addition of RNA. As a medical raw material: nucleotide as a medicine, can inhibit urethral inflammation. |
biological activity | L-Dihydroorotic acid (L-dihydroorotate) is an intermediate of pyrimidine metabolism. It is a substrate for dihydroorotate dehydrogenase (mitochondria). |
Use | used as a freshness enhancer, flavoring agent, can be used for family, |