Name | Iproniazid |
Synonyms | IPRAZID Marsilid iproniazid Iproniazid 1-Isonicotinoyl-2-isopropylhydrazine N'-Isopropylpyridine-4-Carbohydrazide N'-propan-2-ylpyridine-4-carbohydrazide 4-Pyridinecarboxylicacid, 2-(1-methylethyl)hydrazide |
CAS | 54-92-2 |
EINECS | 200-218-8 |
Molecular Formula | C9H13N3O |
Molar Mass | 179.22 |
Density | 1.1305 (rough estimate) |
Melting Point | 112.5-113.5° |
Boling Point | 311.75°C (rough estimate) |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | Pale Beige |
pKa | 11.28±0.23(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
Refractive Index | 1.5100 (estimate) |
Toxicity | An isopropyl derivative of isoniazid that was found to have mood-elevating effects in tuberculosis patients. It was later found to be a monoamine oxidase (MAO) inhibitor and, although not currently approved for clinical use as an antidepressant due to its propensity to cause liver damage it led to the development of other MAO inhibitors currently in use. In addition to hepatotoxic effects, iproniazid is a hypotensive agent and can cause potentially hazardous reactions with other drugs and amine-rich foods. |
biological activity | Iproniazid (Marsilid, Iprazid) is a non-selective and irreversible MAO inhibitor with antidepressant activity. |
Target | Value |