H-SER-LEU-ILE-GLY-ARG-LEU-NH2
H-SER-LEU-ILE-GLY-ARG-LEU-NH2
CAS: 171436-38-7
Molecular Formula: C29H56N10O7
H-SER-LEU-ILE-GLY-ARG-LEU-NH2 - Names and Identifiers
H-SER-LEU-ILE-GLY-ARG-LEU-NH2 - Physico-chemical Properties
| Molecular Formula | C29H56N10O7 |
| Molar Mass | 656.82 |
| Density | 1.34±0.1 g/cm3(Predicted) |
| Appearance | solid |
| pKa | 12.04±0.10(Predicted) |
| Storage Condition | -20°C |
| In vitro study | SLIGRL-NH2 is an agonist of PAR-2 and MrgprC11. SLIGRL-NH2 causes an L-NAME-inhibited relaxation. Based on SLIGRL-NH 2 causing a concentration-dependent relaxation with an EC 50 of 10 µM in endothelium-free preparations in the presence of perivascular adipose tissue (PVAT) , 20 µM is used as a suitable ‘test’ concentration of peptide in subsequent experiments designed to evaluate the effects of potential inhibitors of ADRF release/action. In the endothelium-free aorta preparations, SLIGRL-NH2 causes a concentration-dependent relaxation in preparations only in the presence of PVAT [+PVAT, -ENDO (endothelium)]. |
H-SER-LEU-ILE-GLY-ARG-LEU-NH2 - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
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View History
H-SER-LEU-ILE-GLY-ARG-LEU-NH2
1-[2-(4-氯苯基)-7-甲基吡唑并[1,5-A]嘧啶-6-基]-1-乙酮
2-(METHYLAMINO)-3-PHENYLPROPANOIC ACID
Phenoxyacetic acid 2-[(2-cyanoethyl)[4-[(2-cyano-4-nitrophenyl)azo]phenyl]amino]ethyl ester
DL-GAMMA-AMINO-B-HYDROXYBUTYRIC ACIDCRYS TALLINE
Ethyl 4-(4-formyl-3-hydroxyphenoxy)
2-(2-溴苯基)-5-氯-4H-苯并[d][1,3]恶嗪-4-酮
N-Succinyl-Ala-Ala-Val-Ala P-Nitroanilide
7-Oxabicyclo[4.1.0]heptan-3-ylmethyl acrylate
Isoviral
1-[2-(4-氯苯基)-7-甲基吡唑并[1,5-A]嘧啶-6-基]-1-乙酮
2-(METHYLAMINO)-3-PHENYLPROPANOIC ACID
Phenoxyacetic acid 2-[(2-cyanoethyl)[4-[(2-cyano-4-nitrophenyl)azo]phenyl]amino]ethyl ester
DL-GAMMA-AMINO-B-HYDROXYBUTYRIC ACIDCRYS TALLINE
Ethyl 4-(4-formyl-3-hydroxyphenoxy)
2-(2-溴苯基)-5-氯-4H-苯并[d][1,3]恶嗪-4-酮
N-Succinyl-Ala-Ala-Val-Ala P-Nitroanilide
7-Oxabicyclo[4.1.0]heptan-3-ylmethyl acrylate
Isoviral