Glivenol
Tribenoside
CAS: 10310-32-4
Molecular Formula: C29H34O6
Glivenol - Names and Identifiers
| Name | Tribenoside |
| Synonyms | TBGF Glivenol Glyvenal Glyvenol Hemocuron Tribenoside Tribenzoside 3,5,6-tri-O-benzyl-D-glucofuranoside Glucofuranoside, ethyl 3,5,6-tri-O-benzyl- (7CI) Glucofuranoside, ethyl 3,5,6-tri-O-benzyl-, D- (8CI) (3R,4R,5R)-4-benzyloxy-5-(1,2-dibenzyloxyethyl)-2-ethoxy-tetrahydrofuran-3-ol (2R,3R,4R,5R)-4-benzyloxy-5-(1,2-dibenzyloxyethyl)-2-ethoxy-tetrahydrofuran-3-ol |
| CAS | 10310-32-4 |
| EINECS | 233-687-2 |
| InChI | InChI=1/C29H34O6/c1-2-32-29-26(30)28(34-20-24-16-10-5-11-17-24)27(35-29)25(33-19-23-14-8-4-9-15-23)21-31-18-22-12-6-3-7-13-22/h3-17,25-30H,2,18-21H2,1H3/t25?,26-,27-,28-,29-/m1/s1 |
| InChIKey | ULLNJSBQMBKOJH-VIVFLBMVSA-N |
Glivenol - Physico-chemical Properties
| Molecular Formula | C29H34O6 |
| Molar Mass | 478.58 |
| Density | 1.19±0.1 g/cm3(Predicted) |
| Boling Point | bp1.2 270-280° |
| Specific Rotation(α) | D26 +8° (chloroform) |
| Flash Point | 328.1°C |
| Solubility | Practically insoluble in water, very soluble in acetone, in methanol and in methylene chloride. |
| Vapor Presure | 3.55E-16mmHg at 25°C |
| Appearance | neat |
| Color | Pale Yellow to Light Yellow |
| pKa | 13.01±0.70(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| Refractive Index | 1.59 |
Glivenol - Risk and Safety
| Toxicity | LD50 oral in rat: > 20gm/kg |
Glivenol - Reference Information
| Introduction | Tribenoside (TBS), ethyl -3,5, 6-tribenzyloxy-D-glucoside, consisting of two optical isomers (α-ethyl-3, 5, 6-tribenzyloxy-d-furanglucoside) and β-form (β-ethyl-3, 5, 6-tribenzyloxy-d-furanglucoside) composition of the mixture. The drug was discovered and synthesized in the fifties of last century, and was first developed by Japan in 1999 as an oral drug for the treatment of hemorrhoids. Because of its strong fat solubility, it is easy to be absorbed by the small intestine, and the drug utilization rate is high, therefore, its clinical efficacy is greatly improved compared with other similar drugs. |
| pharmacological effects | It has anti-inflammatory, anti-toxin, enhance capillary toughness, the effect of protecting the wound tissue and promoting its healing and the weak analgesic effect, combined with sphingosine, can prevent gram negative and positive bacteria. |
Last Update：2024-04-09 20:52:54
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View History
Glivenol
180285-25-0
1120-36-1
1-(sec-butyl)-4-(2-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one
(3beta,5beta)-3,5,14-Trihydroxycard-20(22)-enolide
1,1,1-trimethyl-N-(trimethylsilyl)-N-[(trimethylsilyl)oxy]silanamine
3-Dodecyl-1-methyl-1H-imidazolium sulfate
Sifrol
3-[(methylamino)methyl]-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-8-one dihydrochloride
126572-74-5
180285-25-0
1120-36-1
1-(sec-butyl)-4-(2-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one
(3beta,5beta)-3,5,14-Trihydroxycard-20(22)-enolide
1,1,1-trimethyl-N-(trimethylsilyl)-N-[(trimethylsilyl)oxy]silanamine
3-Dodecyl-1-methyl-1H-imidazolium sulfate
Sifrol
3-[(methylamino)methyl]-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-8-one dihydrochloride
126572-74-5