GF4
1F-fructofuranosylnystose
CAS: 59432-60-9
Molecular Formula: C30H52O26
GF4 - Names and Identifiers
GF4 - Physico-chemical Properties
| Molecular Formula | C30H52O26 |
| Molar Mass | 828.72 |
| Density | 1.87±0.1 g/cm3(Predicted) |
| Boling Point | 1227.3±65.0 °C(Predicted) |
| Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
| Appearance | White crystalline powder |
| pKa | 12.76±0.70(Predicted) |
| Storage Condition | 2-8 ℃, stored in nitrogen |
| MDL | MFCD28064306 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from sugarcane, Morinda officinalis. |
| In vitro study | Fructooligosaccharides (FOSs), as a mixture of 1-kestose, nystose, and 1F-fructofuranosylnystose oligosaccharides, exhibit lots of beneficial effects on our health and have been used as food ingredients. |
GF4 - Reference
| Reference Show more | 1. Yang Li, Liu, Mengyun, Feng Chong, et al. Dynamic changes of oligosaccharide content in Morinda officinalis how with different cultivation years and harvest time [J]. New drugs of traditional Chinese medicine and clinical pharmacology 2020 v.31;No.170(05):108-111. 2. Yang Li, Sun Min, Feng Chong, etc. Distribution of six oligosaccharides in different parts of Morinda officinalis [J]. Chinese traditional medicines, 2020, v.42(04):151-155. 3. [IF = 6.953] Min Bao et al."Identification, soluble expression, and characterization of a novel endo-inulinase from Lipomyces starkeyi NRRL Y-11557."Int J Biol Macromol. 2019 Sep;137:537 4. [IF=4.27] Mengyun Liu et al."Transcriptome analysis reveals important candidate gene families related to oligosaccharides biosynthesis in Morinda officinalis."Plant Physiol Bioch. 2021 Oct;167:1061 |
GF4 - Reference Information
| Introduction | fructooligosaccharides, also known as fructooligosaccharides (FOS), refer to 1-5 fructosyl groups as β-2, fructose trisaccharide (GF2), fructose tetrasaccharide (GF3), and fructose pentasaccharide (GF4) formed by the linkage of 1 bond to the D-fructose group of sucrose and a mixture of fructose hexaose (GF5). It is a natural active ingredient in fruits, vegetables, honey and other substances, is an excellent water soluble dietary fiber. Fructooligosaccharides as a representative of prebiotics, in addition to the physical and chemical properties of general functional oligosaccharides, the most striking physiological characteristics is that it can significantly improve the proportion of microbial populations in the intestine, with laxative, enhance immunity, promote the absorption of minerals, improve the intestinal flora, dual phase regulation of micro ecological balance of the "whole intestine" physiological function. |
| Product description | the sweetness of sucrose is 0.3-0.6 times, it is a kind of sweet and delicious functional food ingredients, it is recognized worldwide for its safety and significant function. Fructooligosaccharides have excellent physiological functions, so they are widely used as health food ingredients. In our country, fructooligosaccharides are also used as food ingredients and nutrition enhancers. However, the preparation of high purity fructose monomer is very difficult, which makes it difficult to control the quality of related products. |
| Application | 1) for umbilical cord mesenchymal stem cell culture. Pentasaccharide may increase the proliferation activity of umbilical cord mesenchymal stem cells in vitro by up-regulating sirt2 gene expression. 2) preparation of prebiotics for teeth, fresh breath. Prebiotics have more prominent than P-type fructooligosaccharides prebiotics efficacy, can play an unexpected teeth, fresh breath effect. 2) fructose pentasaccharide, which is used as a component of fructooligosaccharides contained in beverages and foods, and is used as an analytical standard, a chemical reference substance of traditional Chinese medicine, etc. |
| preparation | a method for preparing fructosan monomer, comprising the following steps:(1) dissolving a sample of fructooligosaccharides in water, filter with a filter membrane to obtain a prepared sample solution;(2) prepare the sample solution by preparative high performance liquid chromatography, collect each fraction, chromatographic conditions: the column is XAmide, the mobile phase is acetonitrile and water, the column temperature is room temperature, the mobile phase speed is 8~12ml/min, the injection volume is 200~300 μl each time, the detector is differential detector or evaporative light scattering detector;(3) the collected fractions were concentrated under reduced pressure and dried to obtain fructose triose, fructose tetrasaccharide and fructose pentasaccharide, respectively. |
| biological activity | 1F-Fructofuranosylnystose can be used to synthesize fructooligosaccharides (FOS). Fructooligosaccharides have many beneficial effects on our health and have been used as a food ingredient. |
| in vitro study | fructio noigosaccarides (FOSs), as a mixture of 1-kestose, nystose, and 1f-fructofurosylnystose oligosaccarides, exhibit lots of beneficial effects on our health and have been used as food effects. |
| Chemical properties | white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from sugarcane, Morinda officinalis. |
Last Update：2024-04-09 20:49:11
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View History
GF4
Pyridine, 2-fluoro-3-[(methylthio)methyl]- (9CI)
2-{3-chloro-2-methyl[(4-methylphenyl)sulfonyl]anilino}-N-(2-isopropylphenyl)acetamide
2-{[1-(prop-2-en-1-ylcarbamoyl)ethyl]sulfanyl}pyridine-3-carboxylic acid
Curcumin Sulfate Sodium Salt
Potassium stearate
3,5-二氨基-N-(3-吡啶甲基)苯甲酰胺
dispersant BZS
[4-(5-bromopyrimidin-2-yl)piperazino](2-thienyl)methanone
Pyridine, 2-fluoro-3-[(methylthio)methyl]- (9CI)
2-{3-chloro-2-methyl[(4-methylphenyl)sulfonyl]anilino}-N-(2-isopropylphenyl)acetamide
2-{[1-(prop-2-en-1-ylcarbamoyl)ethyl]sulfanyl}pyridine-3-carboxylic acid
Curcumin Sulfate Sodium Salt
Potassium stearate
3,5-二氨基-N-(3-吡啶甲基)苯甲酰胺
dispersant BZS
[4-(5-bromopyrimidin-2-yl)piperazino](2-thienyl)methanone