Fmoc-Β-环己基-L-丙氨酸
(S)-N-FMOC-Amino-2-cyclohexyl-propanoic acid
CAS: 135673-97-1
Molecular Formula: C24H27NO4
Fmoc-Β-环己基-L-丙氨酸 - Names and Identifiers
Fmoc-Β-环己基-L-丙氨酸 - Physico-chemical Properties
| Molecular Formula | C24H27NO4 |
| Molar Mass | 393.48 |
| Density | 1.1836 (rough estimate) |
| Melting Point | 125-130°C |
| Boling Point | 517.93°C (rough estimate) |
| Appearance | Solid |
| BRN | 7052264 |
| pKa | 3.91±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.6000 (estimate) |
| MDL | MFCD00065614 |
Fmoc-Β-环己基-L-丙氨酸 - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S35 - This material and its container must be disposed of in a safe way. S44 - S28 - After contact with skin, wash immediately with plenty of soap-suds. S7 - Keep container tightly closed. S4 - Keep away from living quarters. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10 |
| HS Code | 2924 29 70 |
| Hazard Class | IRRITANT |
Fmoc-Β-环己基-L-丙氨酸 - Introduction
N-fluorenylmethoxycarbonyl-3-cyclohexyl-L-alanine, also known as Fmoc-L-3-cyclohexylalanine, is an organic compound. Its nature, use, formulation and safety information are described below.
Nature:
N-fluorenylmethoxycarbonyl-3-cyclohexyl-L-alanine is a solid with a chemical formula of C26H29NO4 and a molecular weight of 423.51. It is a white crystal and can be dissolved in some organic solvents, such as dimethyl sulfoxide and dichloromethane. Stable at room temperature.
Use:
N-fluorenylmethoxycarbonyl-3-cyclohexyl-L-alanine is a commonly used amino acid protecting group. It is commonly used in solid phase synthesis to protect amino groups during peptide synthesis. In addition, it can also be used for the synthesis of peptide fluorescent labels, avidin compounds, fluorescent dyes, etc.
Preparation Method:
N-fluorenylmethoxycarbonyl-3-cyclohexyl-L-alanine is generally prepared using standard chemical synthetic methods. The specific steps include reacting fluorenecyl chloride and L-3-cyclohexyl-alanine under alkaline conditions to generate a product, which is then crystallized and purified.
Safety Information:
N-fluorenylmethoxycarbonyl-3-cyclohexyl-L-alanine is generally a stable and safe compound under normal conditions. However, due to the handling of organic solvents and amino acids involved in the use and preparation of compounds, the manufacturer recommends that appropriate laboratory safety measures, such as wearing gloves, glasses and protective clothing, and maintaining good ventilation conditions. Keep away from ignition and organic matter during use and storage. If ingested or in contact with skin and eyes, wash immediately and seek medical attention.
Nature:
N-fluorenylmethoxycarbonyl-3-cyclohexyl-L-alanine is a solid with a chemical formula of C26H29NO4 and a molecular weight of 423.51. It is a white crystal and can be dissolved in some organic solvents, such as dimethyl sulfoxide and dichloromethane. Stable at room temperature.
Use:
N-fluorenylmethoxycarbonyl-3-cyclohexyl-L-alanine is a commonly used amino acid protecting group. It is commonly used in solid phase synthesis to protect amino groups during peptide synthesis. In addition, it can also be used for the synthesis of peptide fluorescent labels, avidin compounds, fluorescent dyes, etc.
Preparation Method:
N-fluorenylmethoxycarbonyl-3-cyclohexyl-L-alanine is generally prepared using standard chemical synthetic methods. The specific steps include reacting fluorenecyl chloride and L-3-cyclohexyl-alanine under alkaline conditions to generate a product, which is then crystallized and purified.
Safety Information:
N-fluorenylmethoxycarbonyl-3-cyclohexyl-L-alanine is generally a stable and safe compound under normal conditions. However, due to the handling of organic solvents and amino acids involved in the use and preparation of compounds, the manufacturer recommends that appropriate laboratory safety measures, such as wearing gloves, glasses and protective clothing, and maintaining good ventilation conditions. Keep away from ignition and organic matter during use and storage. If ingested or in contact with skin and eyes, wash immediately and seek medical attention.
Last Update：2024-04-10 22:29:15
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View History
Fmoc-Β-环己基-L-丙氨酸
2-aMinocyclohexanone HBr
dl-Tamsulosin hydrochloride
L-Lysine, compd. with 4-[2-[(1R,2R)-2-(2,4-difluorophenyl)-1-methyl-2-[(phosphonooxy)methoxy]-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile (1:1)
Reaxys ID: 27149571
AKOS BC-0449
2-{[(2-fluorophenyl)methyl]amino}-N-(3-methoxypropyl)propanamide
2,4-DIFLUORO-3-METHOXYPHENYLACETIC ACID
6-甲基吡啶-2-硼酸频哪醇酯
BAS 00096155
2-aMinocyclohexanone HBr
dl-Tamsulosin hydrochloride
L-Lysine, compd. with 4-[2-[(1R,2R)-2-(2,4-difluorophenyl)-1-methyl-2-[(phosphonooxy)methoxy]-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile (1:1)
Reaxys ID: 27149571
AKOS BC-0449
2-{[(2-fluorophenyl)methyl]amino}-N-(3-methoxypropyl)propanamide
2,4-DIFLUORO-3-METHOXYPHENYLACETIC ACID
6-甲基吡啶-2-硼酸频哪醇酯
BAS 00096155