Fmoc-Tyr(tBu)-Bt
Fmoc-Tyr(tBu)-Bt
CAS: 1126433-42-8
Molecular Formula: C34H32N4O4
Fmoc-Tyr(tBu)-Bt - Names and Identifiers
Fmoc-Tyr(tBu)-Bt - Physico-chemical Properties
| Molecular Formula | C34H32N4O4 |
| Molar Mass | 560.64 |
| Density | 1.26±0.1 g/cm3(Predicted) |
| Melting Point | 99.0-100.5 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3)) |
| pKa | 9.76±0.46(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD11850165 |
Fmoc-Tyr(tBu)-Bt - Introduction
Fmoc-Tyr(tBu)-Bt(Fmoc-benzyloxycarbonyl-chloroformyl tyrosine tetrabutylbenzophenone) is an organic compound. The following is a description of the compound:
Nature:
Fmoc-Tyr(tBu)-Bt is a white to light yellow solid with high stability. It is relatively stable at room temperature, and its shelf life can be extended by storage under dry and non-light conditions.
Use:
Fmoc-Tyr(tBu)-Bt is commonly used in the synthesis of peptide compounds. It is one of the commonly used Fmoc protecting group reaction reagents in the field of peptide synthesis. It can introduce the Fmoc protecting group by reacting with the amino group on the amino acid residue in the peptide chain, and can be deprotected during the synthesis.
Preparation Method:
Fmoc-Tyr(tBu)-Bt can be prepared by reacting Fmoc-benzyloxycarbonylchloroformyl with Tyr(tBu)-OH in the presence of tetrabutylbenzophenone. After the reaction, appropriate purification and crystallization is required to obtain a pure product.
Safety Information:
Fmoc-Tyr(tBu)-Bt is relatively stable, but it still needs to comply with general laboratory safety practices during operation. Contact with skin and eyes should be avoided to avoid inhalation of its dust or gas. Appropriate personal protective equipment, such as lab gloves, goggles and masks, should be worn during operation. After use, the waste should be properly disposed of and disposed of in accordance with relevant regulations.
Nature:
Fmoc-Tyr(tBu)-Bt is a white to light yellow solid with high stability. It is relatively stable at room temperature, and its shelf life can be extended by storage under dry and non-light conditions.
Use:
Fmoc-Tyr(tBu)-Bt is commonly used in the synthesis of peptide compounds. It is one of the commonly used Fmoc protecting group reaction reagents in the field of peptide synthesis. It can introduce the Fmoc protecting group by reacting with the amino group on the amino acid residue in the peptide chain, and can be deprotected during the synthesis.
Preparation Method:
Fmoc-Tyr(tBu)-Bt can be prepared by reacting Fmoc-benzyloxycarbonylchloroformyl with Tyr(tBu)-OH in the presence of tetrabutylbenzophenone. After the reaction, appropriate purification and crystallization is required to obtain a pure product.
Safety Information:
Fmoc-Tyr(tBu)-Bt is relatively stable, but it still needs to comply with general laboratory safety practices during operation. Contact with skin and eyes should be avoided to avoid inhalation of its dust or gas. Appropriate personal protective equipment, such as lab gloves, goggles and masks, should be worn during operation. After use, the waste should be properly disposed of and disposed of in accordance with relevant regulations.
Last Update：2024-04-09 02:00:57
