fmoc-d-3-iodophenylalanine are commonly used in peptide synthesis and protein engineering in solid phase synthesis. It can be used as a chiral reagent for the synthesis of peptide chains and proteins with specific spatial structures.
The method of preparing fmoc-d-3-iodophenylalanine can be achieved through the following steps:
1. Dissolve Fmoc-D-phenylalanine in anhydrous dimethylformamide (DMF).
2. Add dropwise hydroiodic acid and sulfoxide at room temperature.
3. The reaction mixture is stirred at low temperature for a period of time.
4. Filter the mixture to obtain the product, wash and dry.
Regarding safety information, fmoc-d-3-iodophenylalanine is a chemical and the following matters need to be noted:
1. Avoid inhaling dust or contact with skin and eyes, as it may irritate the respiratory system, skin and eyes.
2. Personal protective equipment, including lab coats, goggles and gloves, should be worn during use.
3. storage should be kept dry and sealed, avoid contact with oxidants, acids, alkalis and other substances.
It is recommended to carefully read the relevant safety data sheet (SDS) and instruction manual before using the fmoc-d-3-iodophenylalanine, and operate in accordance with the safety operating procedures. If you have any questions or accidents, please seek professional medical help immediately.