Fmoc-D-2-(2-Thienyl)-glycine(Fmoc-D-2-(2-Thienyl)-glycine) is an organic compound containing a glycine structure in which a hydrogen atom is replaced by a 2-thienyl group. The following is a description of its nature, use, preparation and safety information:
Nature:
1. Chemical formula: C23H19NO4S
2. molecular weight: 405.47g/mol
3. Appearance: white solid
4. Solubility: Slightly soluble in organic solvents (such as dimethyl sulfoxide, dimethylformamide, etc.), insoluble in water.
Use:
1. Fmoc-D-2-(2-Thienyl)-glycine is commonly used in peptide synthesis in solid phase synthesis.
2. As a kind of amino acid compounds, it plays an important role in peptide, protein synthesis and research.
Preparation Method:
Fmoc-D-2-(2-Thienyl)-glycine can be prepared by synthetic route, the specific steps are as follows:
1.2-thiophenecarboxylic acid is subjected to alkali treatment to prepare sodium 2-thiophenecarboxylate.
2. reacting sodium 2-thiophenecarboxylate with glycine anhydride to generate Fmoc-D-2-(2-Thienyl)-glycine.
Safety Information:
1. Fmoc-D-2-(2-Thienyl)-glycine there is no relevant toxicity data, it is necessary to operate with caution and follow laboratory safety regulations during use and handling.
2. During operation, direct contact with skin and eyes should be avoided, and good ventilation conditions should be maintained.
3. such as accidental contact, should immediately rinse with plenty of water, such as discomfort, should seek medical help.