FMOC-D-2-氨基辛二酸
Octanedioic acid,2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2R)-
CAS: 218457-78-4
Molecular Formula: C23H25NO6
FMOC-D-2-氨基辛二酸 - Names and Identifiers
FMOC-D-2-氨基辛二酸 - Physico-chemical Properties
| Molecular Formula | C23H25NO6 |
| Molar Mass | 411.45 |
| Density | 1.286±0.06 g/cm3(Predicted) |
| Boling Point | 670.9±55.0 °C(Predicted) |
| pKa | 3.89±0.21(Predicted) |
| Storage Condition | Store at 0-5°C |
FMOC-D-2-氨基辛二酸 - Risk and Safety
| Hazard Class | IRRITANT |
FMOC-D-2-氨基辛二酸 - Introduction
Octanedioic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2R)-is a compound whose chemical name is Octanedioic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2R)-. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C23H21NO5
-Molecular weight: 391.42g/mol
-Melting point: 168-170 ° C
-Solubility: Soluble in some organic solvents, such as dichloromethane and dimethyl sulfoxide
Use:
- Octanedioic acid,2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2R)-is an ion exchange resin used as a protecting group in organic synthesis, can be used in peptide synthesis, DNA synthesis and polypeptide purification process.
-It can be used as a protecting group to protect amine groups to prevent unwanted reactions in chemical reactions.
Method: The preparation method of
Octanedioic acid,2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2R)-is usually divided into several steps:
1. First, 2-aminoctanoic acid and dimethylformamide dimethyl lithium sulfite were mixed in toluene, and the mixture was reduced with diborane to obtain methyl 2-aminoctanoate.
2. Next, the obtained methyl 2-aminoctanoate was added to tetrahydrofuran that had been dried, and the mixture was subjected to esterification reaction with FMOC-OSu to obtain methyl FMOC-D-2-aminoctanoate.
3. Finally, methyl FMOC-D-2-aminocaprylate is hydrolyzed under strong acid conditions to give Octanedioic acid,2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2R)-.
Safety Information:
-Follow laboratory safety procedures when handling Octanedioic acid,2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2R).
-This compound may be irritating to the skin, eyes and respiratory tract and contact should be avoided.
-Use appropriate protective equipment such as lab gloves, goggles and face shields during use.
-During storage and handling, avoid contact with strong oxidants and keep them in a dry, cool place.
-In case of accidental contact or inhalation, wash off immediately or seek medical help.
Nature:
-Appearance: White crystalline solid
-Molecular formula: C23H21NO5
-Molecular weight: 391.42g/mol
-Melting point: 168-170 ° C
-Solubility: Soluble in some organic solvents, such as dichloromethane and dimethyl sulfoxide
Use:
- Octanedioic acid,2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2R)-is an ion exchange resin used as a protecting group in organic synthesis, can be used in peptide synthesis, DNA synthesis and polypeptide purification process.
-It can be used as a protecting group to protect amine groups to prevent unwanted reactions in chemical reactions.
Method: The preparation method of
Octanedioic acid,2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2R)-is usually divided into several steps:
1. First, 2-aminoctanoic acid and dimethylformamide dimethyl lithium sulfite were mixed in toluene, and the mixture was reduced with diborane to obtain methyl 2-aminoctanoate.
2. Next, the obtained methyl 2-aminoctanoate was added to tetrahydrofuran that had been dried, and the mixture was subjected to esterification reaction with FMOC-OSu to obtain methyl FMOC-D-2-aminoctanoate.
3. Finally, methyl FMOC-D-2-aminocaprylate is hydrolyzed under strong acid conditions to give Octanedioic acid,2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2R)-.
Safety Information:
-Follow laboratory safety procedures when handling Octanedioic acid,2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2R).
-This compound may be irritating to the skin, eyes and respiratory tract and contact should be avoided.
-Use appropriate protective equipment such as lab gloves, goggles and face shields during use.
-During storage and handling, avoid contact with strong oxidants and keep them in a dry, cool place.
-In case of accidental contact or inhalation, wash off immediately or seek medical help.
Last Update：2024-04-10 22:29:15
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CAS: 218457-78-4
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CAS: 218457-78-4
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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