FMOC-9-氨基-4,7-二噁壬酸
Fmoc-9-Amino-4,7-Dioxanonanoic acid
CAS: 872679-70-4
Molecular Formula: C22H25NO6
FMOC-9-氨基-4,7-二噁壬酸 - Names and Identifiers
FMOC-9-氨基-4,7-二噁壬酸 - Physico-chemical Properties
| Molecular Formula | C22H25NO6 |
| Molar Mass | 399.44 |
| Density | 1.243±0.06 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 95.0 to 99.0 °C |
| Boling Point | 621.0±50.0 °C(Predicted) |
| Solubility | soluble in Methanol |
| Appearance | powder to crystal |
| Color | White to Almost white |
| pKa | 4.28±0.10(Predicted) |
| Storage Condition | 2-8°C |
| In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
FMOC-9-氨基-4,7-二噁壬酸 - Reference Information
| biological activity | Fmoc-NH-PEG2-CH2CH2COOH is a degradable ADC linker used in antibody drug conjugate (ADC) synthesis. Fmoc-NH-PEG2-CH2CH2COOH is also a PEG-based PROTAC linker, which can be used for PROTAC synthesis. |
Last Update：2024-04-09 21:21:28
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FMOC-9-氨基-4,7-二噁壬酸
8-苯氨基-1-萘磺酸铵盐水合物
2-NORBORNANEACETIC ACID
tert-butyl 6-formyl-2-azaspiro[3.3]heptane-2-carboxylate
8-苯氨基-1-萘磺酸铵盐水合物
2-NORBORNANEACETIC ACID
tert-butyl 6-formyl-2-azaspiro[3.3]heptane-2-carboxylate