Fmoc-(S)-3-Amino-4-(4-bromo-phenyl)-butyric is an organic compound, an anhydrous amino-protecting agent commonly used in solid-phase synthetic methods.
Its chemical properties are white solids, the molecular formula is C20H18BrNO3, and the molecular weight is 408.27g/mol. It is a chiral compound with a chiral center. Its CAS number is 136677-38-2.
Fmoc-(S)-3-Amino-4-(4-bromo-phenyl)-butyric acid is mainly used as an anhydrous amino protecting agent in solid phase synthesis. In the synthesis of polypeptides and proteins, amino groups need to be protected to prevent non-specific reactions. By using Fmoc-(S)-3-Amino-4-(4-bromo-phenyl)-butyric acid, the non-specific reaction of the amino group can be effectively prevented, thereby making the synthesis reaction more selective.
The preparation method thereof is usually completed by a synthetic step. First, under appropriate reaction conditions, bromophenylaminobutyric acid was reacted with Fmoc-Cl to obtain Fmoc-(S)-3-Amino-4-(4-bromo-phenyl)-butyric acid. Then, by a suitable purification method, a pure product is obtained.
Regarding safety information, Fmoc-(S)-3-Amino-4-(4-bromo-phenyl)-butyric acid is a chemical and needs to be operated in a laboratory environment. In the process of use, should abide by the safety operation procedures, wear protective glasses and gloves. At the same time, should be stored in a cool, dry place, away from fire and flammable materials. In case of accidental contact or inhalation, seek medical attention immediately and carry the packaging and labeling of the chemical.