Molecular Formula | C17H12ClNO2S |
Molar Mass | 329.8 |
Density | 1.1592 (rough estimate) |
Melting Point | 162°C |
Boling Point | 556.2±60.0 °C(Predicted) |
Water Solubility | 31.66mg/L(25 ºC) |
pKa | 3.89±0.10(Predicted) |
Refractive Index | 1.6100 (estimate) |
Physical and Chemical Properties | Colorless needle crystal. Melting point 161-162 ℃(157-158 ℃). Easily soluble in acetone, slightly soluble in methanol and ethanol, hardly soluble in chloroform and benzene, almost insoluble in water. In case of light, it gradually changes color and is odorless. |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
Toxicity | LD50 in rats, mice (mg/kg): 661, 692 orally (Marmo) |
Use | chlorfenthioacetic acid is a new steroidal anti-inflammatory and inhibitory pain medicine, which can be used for chronic arthritis, osteoarthritis, periarthritis of shoulder, low back pain, inflammation of the respiratory tract anti-inflammatory analgesia, also used for trauma and postoperative, tooth extraction anti-inflammatory analgesia. |
production method | derived from the α-bromination of p-chlorophenylbutane-4 followed by condensation with thiobenzamide. |