Ethyl 4-bromo-alpha,alpha-difluorobenzeneacetate

Ethyl 4-bromo-alpha,alpha-difluorobenzeneacetate - Names and Identifiers

Name	ethyl 2-(4-bromophenyl)-2,2-difluoroacetate
Synonyms	ethyl 2-(4-bromophenyl)-2,2-difluoroacetate ETHYL 2-(4-BROMOPHENYL)-2,2-DIFLUOROACETATE Ethyl 4-bromo-alpha,alpha-difluorobenzeneacetate 2-(4-Bromophenyl)-2,2-difluoroacetic acid ethyl ester Benzeneacetic acid, 4-bromo-α,α-difluoro-, ethyl ester
CAS	1004305-97-8

Ethyl 4-bromo-alpha,alpha-difluorobenzeneacetate - Physico-chemical Properties

Molecular Formula	C10H9BrF2O2
Molar Mass	279.08
Density	1.494±0.06 g/cm3(Predicted)
Boling Point	296.0±35.0 °C(Predicted)
Storage Condition	Sealed in dry,2-8°C
Sensitive	IRRITANT
MDL	MFCD11975615

Ethyl 4-bromo-alpha,alpha-difluorobenzeneacetate - Introduction

ethyl 2-(4-bromophenyl)-2,2-difluoroacetate is an organic compound with the chemical formula C10H8BrF2O2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless to light yellow liquid
-Solubility: Soluble in organic solvents such as ether and dichloromethane
-Boiling point: About 155-160 degrees Celsius
-Density: approx. 1.65g/cm³
-The compound has a strong pungent odor

Use:
- ethyl 2-(4-bromophenyl)-2,2-difluoroacetate is commonly used as an intermediate in the synthesis of drugs, pesticides or dyes.
-Because of its good reactivity, it can be used for esterification and acylation reactions in organic synthesis.

Method:
-A common preparation method is to react p-bromobenzoic acid and ethyl difluoroacetate under alkaline conditions to form ethyl 2-(4-bromophenyl)-2,2-difluoroacetate through transesterification.

Safety Information:
- ethyl 2-(4-bromophenyl)-2,2-difluoroacetate is an organic compound and should be handled with caution in a laboratory environment.
-It may cause irritation to the eyes, skin and respiratory tract, so use appropriate personal protective equipment, such as glasses, gloves and protective masks.
-Avoid inhaling its vapors or contacting its liquids to ensure good ventilation.
-When disposing of waste, follow local regulations and properly classify and dispose of waste.

Last Update：2024-04-09 21:04:16