ethyl 2-(4-bromophenyl)-2,2-difluoroacetate is an organic compound with the chemical formula C10H8BrF2O2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to light yellow liquid
-Solubility: Soluble in organic solvents such as ether and dichloromethane
-Boiling point: About 155-160 degrees Celsius
-Density: approx. 1.65g/cm³
-The compound has a strong pungent odor
Use:
- ethyl 2-(4-bromophenyl)-2,2-difluoroacetate is commonly used as an intermediate in the synthesis of drugs, pesticides or dyes.
-Because of its good reactivity, it can be used for esterification and acylation reactions in organic synthesis.
Method:
-A common preparation method is to react p-bromobenzoic acid and ethyl difluoroacetate under alkaline conditions to form ethyl 2-(4-bromophenyl)-2,2-difluoroacetate through transesterification.
Safety Information:
- ethyl 2-(4-bromophenyl)-2,2-difluoroacetate is an organic compound and should be handled with caution in a laboratory environment.
-It may cause irritation to the eyes, skin and respiratory tract, so use appropriate personal protective equipment, such as glasses, gloves and protective masks.
-Avoid inhaling its vapors or contacting its liquids to ensure good ventilation.
-When disposing of waste, follow local regulations and properly classify and dispose of waste.