Di(1-adamantyl)-1-piperidinylphenylphosphine - Names and Identifiers
Di(1-adamantyl)-1-piperidinylphenylphosphine - Physico-chemical Properties
Molecular Formula | C31H44NP
|
Molar Mass | 461.67 |
Melting Point | 225-230℃ |
Storage Condition | Room Temprature |
MDL | MFCD28053539 |
Di(1-adamantyl)-1-piperidinylphenylphosphine - Risk and Safety
Di(1-adamantyl)-1-piperidinylphenylphosphine - Introduction
2-(Di-1-adamantylphosphino)phenylpiperidine, chemical formula C43H58NP, is an organic compound. Its nature is as follows:
1. Appearance: 2-(Di-1-adamantylphosphino)phenylpiperidine is white to light yellow crystalline or crystalline powder.
2. Melting Point: about 130-135 degrees Celsius.
3. Solubility: Soluble in non-polar solvents, such as chloroform, dimethyl sulfoxide and ether.
2-(Di-1-adamantylphosphino)phenylpiperidine has important applications in organic synthesis, mainly used as a ligand for coordination compound catalysts. It can coordinate with metal catalysts to form stable complexes, and is widely used in asymmetric catalysis, reduction reaction, hydrogenation reaction and other organic synthesis processes to improve the selectivity and effect of the reaction.
The preparation method of
2-(Di-1-adamantylphosphino)phenylpiperidine is generally realized by synthetic reaction, and the specific steps are as follows:
1. First, under appropriate conditions, adamantan-1-ol is reacted with bromoacetonitrile to obtain adamantan-1-bromoacetonitrile.
2. Reacting adamantane -1-Bromo acetonitrile with phenyl alcohol to generate adamantyl phenyl ether.
3. In the presence of adamantyl phenyl ether, 2-piperidinamine reacts with triphenylphosphine to generate 2-(Di-1-adamantylphosphino)phenylpiperidine.
It should be noted that the reaction conditions and operation safety should be strictly controlled in the synthesis to avoid chemical leakage and harm.
Regarding the safety information of 2-(Di-1-adamantylphosphino)phenylpiperidine, it is a chemical and has a certain degree of danger. When using or storing, the following precautions should be observed:
1. Avoid skin contact and inhalation, avoid ingestion. Appropriate protective gloves, goggles and face shields should be worn during operation.
2. During operation, ensure good ventilation.
3. Avoid contact with oxidizing agent strong acid and other substances to prevent dangerous reaction.
4. When storing, it should be stored in a low-temperature, dry and sealed container, away from fire and heat sources.
5. In case of accidental contact or inhalation, rinse immediately with plenty of water and seek medical assistance.
These are related introductions to the nature, use, formulation and safety information of 2-(Di-1-adamantylphosphino)phenylpiperidine.
Last Update:2024-04-10 22:29:15