DAHP
2,4-Diamino-6-hydroxypyrimidine
CAS: 56-06-4
Molecular Formula: C4H6N4O
DAHP - Names and Identifiers
| Name | 2,4-Diamino-6-hydroxypyrimidine |
| Synonyms | DAHP 2,6-Diamino-4-pyrimidinol 2,6-Diamino-4-pyrimidinone 2,6-Diamino-4-Hydroxyprimidine 2,6-diaminopyrimidin-4(1H)-one 2,4-Diamino-6-hydroxypyrimidine 2,4-Diamino-6-hydroxypyrimidine monohydrate |
| CAS | 56-06-4 |
| EINECS | 200-254-4 |
| InChI | InChI=1/C4H6N4O.H2O4S/c5-2-1-3(9)8-4(6)7-2;1-5(2,3)4/h1H,(H5,5,6,7,8,9);(H2,1,2,3,4) |
DAHP - Physico-chemical Properties
| Molecular Formula | C4H6N4O |
| Molar Mass | 126.12 |
| Melting Point | 285-286℃ |
| Boling Point | 288.5°C at 760 mmHg |
| Flash Point | 128.3°C |
| Vapor Presure | 0.00232mmHg at 25°C |
| Appearance | Yellow needle crystal |
| Storage Condition | 2-8℃ |
| MDL | MFCD00006098 |
| Physical and Chemical Properties | Characteristic yellow needle-like crystals. Melting Point: 260-270 ℃ |
| Use | Used as a pharmaceutical Intermediate |
DAHP - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
DAHP - Nature
Open Data Verified Data
yellow needle Crystal (acetic acid) or crystal (water), containing 1 mol of crystal water, melting point 285~286 C (decomposition).
Last Update：2024-01-02 23:10:35
DAHP - Preparation Method
Open Data Verified Data
guanidine nitrate was heated and stirred in sodium methoxide (or 50% NaOH) and refluxed for half an hour, then methyl cyanoacetate was added dropwise and refluxed for 2 hours. After completion of the reaction, methanol was recovered by heating. The residue was dissolved by adding hot water. When the heating temperature reached 80 ℃, acetic acid was added to adjust pH = 8, and the product was crystallized, cooled to below 20 ℃, filtered, washed and dried.
Last Update：2022-01-01 10:53:21
DAHP - Use
Open Data Verified Data
The synthetic intermediates such as cancer-M, chlorpromazine, folic acid, acyclovir, ganciclovir, etc. Also used for nitrate (ester) or nitrite (ester) determination.
Last Update：2022-01-01 10:53:21
DAHP - Safety
Open Data Verified Data
- low toxicity. Operators should wear protective gear.
- lined with plastic bag, external woven bag packaging. Store in a cool, ventilated, dry place, sunscreen, moisture, away from fire, heat source. Light loading and light unloading should be carried out to avoid package breakage.
Last Update：2022-01-01 10:53:22
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View History
DAHP
Benzamide, N-[2-[(3S)-3-[[cis-4-hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl]amino]-1-pyrrolidinyl]-2-oxoethyl]-3-(triflu
[5-(4-CHLOROPHENYL)-1-(2,5-DICHLOROPHENYL)-1H-PYRAZOL-3-YL](MORPHOLINO)METHANONE
ROSEMARY OIL, SPANISH
7H-Benz[de]anthracen-7-one
2,2,2-三氟-1-(4-异丙基环己基)乙-1-胺
74474-06-9
4-[4-METHYL-2-(METHYLSULFANYL)-5,6-DIHYDRO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL]BENZENOL
Calycosin-7-O-beta-D-glucoside
188569-30-4
Benzamide, N-[2-[(3S)-3-[[cis-4-hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl]amino]-1-pyrrolidinyl]-2-oxoethyl]-3-(triflu
[5-(4-CHLOROPHENYL)-1-(2,5-DICHLOROPHENYL)-1H-PYRAZOL-3-YL](MORPHOLINO)METHANONE
ROSEMARY OIL, SPANISH
7H-Benz[de]anthracen-7-one
2,2,2-三氟-1-(4-异丙基环己基)乙-1-胺
74474-06-9
4-[4-METHYL-2-(METHYLSULFANYL)-5,6-DIHYDRO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL]BENZENOL
Calycosin-7-O-beta-D-glucoside
188569-30-4