Molecular Formula | C27H41N9O8 |
Molar Mass | 619.67 |
Storage Condition | -20 ℃, sealed, dry |
In vitro study | Cyclo(RGDyK) (c(RGDyK(SAA)) shows high affinity and selectivity for α V β 3 over α V β 5 (IC 50 =4000 nM) and α IIb β 3 (IC 50 =3000 nM). |
biological activity | Cyclo(RGDyK) is a potent and selective inhibitor of αVβ3 integrin, the IC50 was 20 nM. |
Target | IC50: 20 nM (αv β 3 Integrin), 3000 nM (αiib β 3 Integrin), 4000 nM (αvβ5 Integrin) |