CP-10
CP-10
CAS: 2366268-80-4
Molecular Formula: C44H49N13O7
CP-10 - Names and Identifiers
| Name | CP-10 |
| Synonyms | CP-10 1,2,3,4,5,6,7,8,9-NONACHLORODECANE |
| CAS | 2366268-80-4 |
CP-10 - Physico-chemical Properties
| Molecular Formula | C44H49N13O7 |
| Molar Mass | 871.94 |
| Storage Condition | -20°C，干燥，密封 |
| In vitro study | CP-10 induces nearly 72% degradation of CDK6 at 10 nM and 89% at 100 nM in human glioblastoma U251 cells. The degradation of CDK4 induced by CP-10 is far weaker than that of CDK6 (DC 50 : 50-80 fold). CP-10 displays a cell inhibition potential in multiple myeloma cell MM.1S (IC 50 ≈10 nM) and mantle cell lymphoma cells (in Mino, IC 50 ≈8 nM). |
CP-10 - Reference Information
| biological activity | CP-10 is characterized by high selectivity, specificity and significant CDK6 degradation potential (DC50=2.1 nM). PROTAC. It inhibits proliferation of several hematopoietic cell cancers, including multiple myeloma, and can still degrade mutant and overexpressed CDK6. |
Last Update：2024-04-09 21:01:54
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Product Name: CP-10 Visit Supplier Webpage Request for quotationCAS: 2366268-80-4
Tel: +86-400-900-4166
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QQ: 2881950922
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View History
CP-10
2-[(1,1-DIMETHYLETHYL) AMINO]-1-[4-OH-3-(HYDROXYMETHYL)PHENYL]ETHAN-1-ONE
2-MERCAPTO-5-N-PROPYLPYRIMIDINE
Dextropropoxyphene Hydrochloride Impurity F as Hydrochloride
Phosphorodithioic acid S-[2-[di(isopropyloxy)phosphinylamino]ethyl]O,O-dimethyl ester
2-溴-5-甲氧基苯硫醇
Einecs 266-070-1
3-pyridazinol, 4-methyl-
Hc Yellow No. 2
β-L-lyxo-Hex-5-enofuranose, 6,6-dibromo-5,6-dideoxy-1,2-O-(1-methylethylidene)-4-C-[(phenylmethoxy)methyl]-3-O-(phenylmethyl)-
2-[(1,1-DIMETHYLETHYL) AMINO]-1-[4-OH-3-(HYDROXYMETHYL)PHENYL]ETHAN-1-ONE
2-MERCAPTO-5-N-PROPYLPYRIMIDINE
Dextropropoxyphene Hydrochloride Impurity F as Hydrochloride
Phosphorodithioic acid S-[2-[di(isopropyloxy)phosphinylamino]ethyl]O,O-dimethyl ester
2-溴-5-甲氧基苯硫醇
Einecs 266-070-1
3-pyridazinol, 4-methyl-
Hc Yellow No. 2
β-L-lyxo-Hex-5-enofuranose, 6,6-dibromo-5,6-dideoxy-1,2-O-(1-methylethylidene)-4-C-[(phenylmethoxy)methyl]-3-O-(phenylmethyl)-