Name | CP-060 |
Synonyms | CP 060 CP-060 4-Thiazolidinone, 3-[3-[[2-(1,3-benzodioxol-5-yloxy)ethyl]methylamino]propyl]-2-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]- |
CAS | 180090-15-7 |
Molecular Formula | C30H42N2O5S |
Molar Mass | 542.74 |
Density | 1.174±0.06 g/cm3(Predicted) |
Melting Point | 70-71 °C |
Boling Point | 633.6±55.0 °C(Predicted) |
pKa | 11.53±0.50(Predicted) |
Storage Condition | -20℃ |
In vitro study | CP-060 (0.5, 5 μM) inhibits rabbit LDL oxidation induced by soybean lipoxygenase by 12.9% and 3.0%, respectively. |
In vivo study | CP-060 (100 mg/kg, i.v.) increases the coronary blood flow by 96% in anesthetized dogs. |
biological activity | CP- 060 is a Ca2 antagonist, which can inhibit Ca2 overload, the role of protection of the heart. |