Molecular Formula | C23H25Cl2N3 |
Molar Mass | 414.37 |
Density | 1.22±0.1 g/cm3(Predicted) |
Boling Point | 528.3±50.0 °C(Predicted) |
Solubility | 10 mM in DMSO |
pKa | 7.60±0.10(Predicted) |
Storage Condition | -20℃ |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.413 ml | 12.066 ml | 24.133 ml |
5 mM | 0.483 ml | 2.413 ml | 4.827 ml |
10 mM | 0.241 ml | 1.207 ml | 2.413 ml |
5 mM | 0.048 ml | 0.241 ml | 0.483 ml |
biological activity | BM212 is an effective mycobacterial membrane protein MmpL3 inhibitor. BM212 has strong inhibitory activity against Mycobacterium tuberculosis and some non-tuberculosis mycobacteria. The MIC value of BM212 strain H37Rv against Mycobacterium tuberculosis was 5 µM. |
target | M. tuberculosis |