Artesunate-d4 - Names and Identifiers
Name | Artesunate-d4
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Synonyms | Artesunate-d4 Artesunic Acid-d4 Butanedioic Acid Mono(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-triMethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] Ester-d4
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CAS | 1316753-15-7
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Artesunate-d4 - Physico-chemical Properties
Molecular Formula | C19H28O8
|
Molar Mass | 384.42082 |
Melting Point | 137-139°C |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | White |
Storage Condition | -20°C Freezer |
Artesunate-d4 - Introduction
Artesunate-d4 (Artesunate-d4) is an organic compound, is the reference substance (internal standard), the chemical formula is C19H28D4O8. It is a deuterated derivative of Artesunate (artemisinin pregnant) with similar properties.
Artesunate-d4 is mainly used to prepare internal standards in pharmacokinetic studies, and is used to detect the concentration changes of Artesunate during drug metabolism. It can be used for in vitro or in vivo pharmacokinetic experiments to help researchers assess the rate of metabolism and elimination of a drug.
The preparation method of the compound can be obtained by synthesizing Artesunate, using deuterated reagent or deuterated agent for nuclear substitution reaction, and replacing a certain number of deuterated atoms with hydrogen atoms in Artesunate molecules.
Regarding safety information, Artesunate-d4 there is currently no separate safety data, since it is a deuterated derivative of Artesunate, you can refer to the safety information of Artesunate. Artesunate is widely used in anti-malaria drugs. It is generally believed that it has good safety at normal doses, but some adverse reactions may occur in individual cases, such as nausea, vomiting, and headache. When using Artesunate or its deuterated derivatives, you should follow the recommendations of your doctor and follow the instructions for the drug.
It is important to note that Artesunate-d4 is a laboratory compound, for scientific use only, not for human or animal drug treatment. In the working environment, use should comply with the relevant laboratory safety regulations, avoid direct contact with the skin and inhalation of gas.
Last Update:2024-04-09 21:04:16