Arterolane(OZ277
Arterolane
CAS: 664338-39-0
Molecular Formula: C22H36N2O4
Arterolane(OZ277 - Names and Identifiers
| Name | Arterolane |
| Synonyms | OZ 277 RBx 11160) Arterolane ARTEROLANE Arterolane(OZ277 -tricyclo[3.3.1.13,7]decane]-4-acetamide Dispiro[cyclohexane-1,3'-[1,2,4]trioxolane-5',2''-tricyclo[3.3.1.13,7]decane]-4-acetamide, N-(2-amino-2-methylpropyl)-, cis- |
| CAS | 664338-39-0 |
Arterolane(OZ277 - Physico-chemical Properties
| Molecular Formula | C22H36N2O4 |
| Molar Mass | 392.53 |
| Density | 1.20 |
| Melting Point | 160-162℃ |
| Boling Point | 572.2±45.0 °C(Predicted) |
| pKa | 16.70±0.46(Predicted) |
| Storage Condition | 2-8℃ |
| In vitro study | Arterolane (Trioxolane 7; OZ277; RBx-11160) is an antimalarial agent, with IC 50 s of both 1.1 nM (0.43 ng/mL) against P. falciparum Ro73 and W2, respectively. Arterolane also shows inhibitory activity against several other P. falciparum s, with IC 50 s of 1.0, 1.6, 0.90, 0.91, 1.4, 1.5, 0.83, and 0.84 ng/mL for P. falciparum K1, Fc27, FVO, NF54, HB3, FCB1, ITG2-F6, and MAD20, respectively. |
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View History
Arterolane(OZ277
3-苯基菲
双胍三辛烷基苯磺酸盐,100PPM
Cyclomide CP
19-Norcholest-9-ene-3,6-diol,5-methyl-, diacetate, (3b,5b,6b)- (9CI)
1-(2,4-二丙氧基苯基)乙-1-酮
3-苯基菲
双胍三辛烷基苯磺酸盐,100PPM
Cyclomide CP
19-Norcholest-9-ene-3,6-diol,5-methyl-, diacetate, (3b,5b,6b)- (9CI)
1-(2,4-二丙氧基苯基)乙-1-酮