ALPHA-甲基-4-(2-甲基丙基)苯乙醛
2-(4-isobutylphenyl)propionaldehyde
CAS: 51407-46-6
Molecular Formula: C13H18O
ALPHA-甲基-4-(2-甲基丙基)苯乙醛 - Names and Identifiers
ALPHA-甲基-4-(2-甲基丙基)苯乙醛 - Physico-chemical Properties
| Molecular Formula | C13H18O |
| Molar Mass | 190.28 |
| Density | 0.937±0.06 g/cm3(Predicted) |
| Boling Point | 64-65 °C(Press: 0.2 Torr) |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Appearance | Oil |
| Color | Colourless |
| Storage Condition | Hygroscopic, Refrigerator, under inert atmosphere |
| Stability | Hygroscopic |
| Physical and Chemical Properties | Liquid. Boiling point 120-130 ℃/1.09kPa. |
ALPHA-甲基-4-(2-甲基丙基)苯乙醛 - References
| Use | intermediate for ibuprofen. |
| production method | 4-isobutylacetophenone is formed by reacting isobutylbenzene with Chloroacetyl in the presence of anhydrous aluminum trichloride. The latter was then condensed with ethyl chloroacetate in the presence of sodium isopropoxide to give ethyl 3-(4-isobutylphenyl)-2, 3-epoxybutanoate, further, the product was prepared by hydrolyzing sodium 3-(4-isobutylphenyl)-2, 3-epoxybutyrate with sodium hydroxide solution, and finally acidifying and decarboxylating. |
Last Update：2024-04-09 15:17:17
