AIDS-028443
Chymostatin
CAS: 9076-44-2
Molecular Formula: C92H121N21O18
AIDS-028443 - Names and Identifiers
AIDS-028443 - Physico-chemical Properties
| Molecular Formula | C92H121N21O18 |
| Molar Mass | 1809.08 |
| Melting Point | 205 °C |
| Solubility | DMSO: 10mM Stock solutions stable for months at −20 °C. |
| Appearance | White to slightly yellow solid or powder |
| Color | White or off-white |
| Storage Condition | -20°C |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. |
AIDS-028443 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| RTECS | GC3047700 |
| FLUKA BRAND F CODES | 10-21 |
AIDS-028443 - Reference Information
| effect | chymotrypsin inhibitors can also reduce the degradation of proteins in the intestine, resulting in the production of amino acids and peptides being affected, thereby affecting the normal metabolism of organisms. |
| application | chymotrypsin inhibitor (ChymotrypsinInhibitor,CI) widely exists in microorganisms, legumes, gramineous plants, arthropods and mammals, and its main function is to stop, prevent or reduce chymotrypsin activity. |
| preparation | preparation of potato chymotrypsin inhibitor includes the following steps: ① extraction: fresh potatoes are washed and chopped and soaked in 7g/l sodium disulfite aqueous solution for 30 minutes. remove the supernatant, add 50 ml of the same solution into the tube, put it into a tissue masher and stir until homogenate. Filter, adjust the filtrate to pH3.0, centrifuge, and collect the centrifugal liquid. ② salt folding: at 5 ℃, add solid sulfuric acid to the centrifugal solution to 70% saturation, stir for l hours, centrifuge and precipitate sulfuric acid suspended in the same saturation, filter and wash with whatmaln filter paper at room temperature. The precipitate is dissolved in distilled water and stirred, filtered, and the filtrate is retained. ③ heat treatment: the filtrate is placed in a 70 ℃ water bath for 5 minutes, filtered, and the filtrate is to be dialyzed. ④ transparent folding: the filtrate is put into the transparent folding bag, and the distilled water is folded in the refrigerator for 48 hours, during which the distilled water is replaced several times. Filtration, freeze-drying of the filtrate into powder. ⑤ separation: 0.05M,pHs.ZTris · HCI starting buffer (containing 0.1MKCI) is used for hot dissolution of SephadexG-75 gel, and the column (20x 50cm) is loaded after debubble under reduced pressure. Balance. 20 mg frozen dry powder dissolved in 5 ml buffer, centrifuged, on column. Eluted with starting buffer at a flow rate of 60 ml/hour, and collected 5 ml by division. Measure the light absorption value of each tube collection liquid at 280cm to obtain the elution curve. Peak I and peak l were collected respectively and freeze dried. |
Last Update：2024-04-09 20:52:54
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CAS: 9076-44-2
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Product Name: Chymostatin Visit Supplier Webpage Request for quotation
CAS: 9076-44-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 9076-44-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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