ACA-PEG-SC - Names and Identifiers
ACA-PEG-SC - Physico-chemical Properties
ACA-PEG-SC - Introduction
ACA-PEG-NHS(ACA-PEG-NHS) is a commonly used chemical reagent with the following properties and uses:
Properties: ACA-PEG-NHS is a white or yellowish solid, soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and dimethyl formamide (DMF). It has good thermal stability and chemical stability.
Uses: ACA-PEG-NHS are mainly used for covalent modification and functionalization in the field of biochemistry. It can react with amino acids or hydroxyl groups in proteins to form ester bonds, thereby achieving protein PEGylation (polyethylene glycol modification). By introducing polyethylene glycol molecules, the stability of the protein can be increased, the immunogenicity can be reduced and the half-life can be prolonged. In addition, ACA-PEG-NHS can also be used to modify drugs, synthetic polymers and other fields.
Preparation method: The preparation of ACA-PEG-NHS usually adopts the method of chemical synthesis. First, an acrylamide polymer is mixed with polyethylene glycol in a certain ratio, and an activating agent, such as N-hydroxysuccinimide (NHS), is added. The reaction is carried out at a certain temperature and reaction time to form ACA-PEG-NHS. Finally, unreacted raw materials and by-products are removed by a purification step to obtain a pure ACA-PEG-NHS product.
Safety information: ACA-PEG-NHS is generally considered to be a relatively safe chemical reagent, but it still needs to be handled and stored correctly. It should be kept away from fire sources and oxidants, and should be used in a well-ventilated area. Avoid contact with skin and eyes, and wear protective gloves and goggles if necessary. If you take it by mistake or inhale it by mistake, please seek medical attention in time. The safety data sheet and instructions for use provided with the product should be carefully read before use.
Last Update:2024-04-09 21:01:54