Name | (1E)-1,2-diphenylethanone oxime |
Synonyms | SC-66276 NSC 36666 NSC 135001 DeoxyBenzoinOxime Parecoxib Impurity 2 Benzyl phenyl ketoxime α-Phenylacetophenone oxime Ethanone,1,2-diphenyl-, oxime Ethanone, 1,2-diphenyl-, oxime (1E)-1,2-diphenylethanone oxime (1E)-1,2-diphenylethanone oxiMe (Parecoxib sodiuM inteMediate) |
CAS | 952-06-7 |
EINECS | 811-357-4 |
InChI | InChI=1/C14H13NO/c16-15-14(13-9-5-2-6-10-13)11-12-7-3-1-4-8-12/h1-10,16H,11H2/b15-14+ |
Molecular Formula | C14H13NO |
Molar Mass | 211.26 |
Density | 1.04±0.1 g/cm3 (20 ºC 760 Torr) |
Melting Point | 98℃ |
Boling Point | 375.4±21.0 °C(Predicted) |
Flash Point | 238°C |
Vapor Presure | 2.65E-06mmHg at 25°C |
pKa | 11.07±0.11(Predicted) |
Storage Condition | 2-8℃ |
Refractive Index | 1.562 |
Overview | parecoxib is a specific inhibitor of cyclooxygenase-2 (COX -2), it is a prodrug of Valdecoxib and belongs to the class of coxib analgesics among the anti-arthritic drugs. Parecoxib is used for short-term treatment of postoperative pain. The sodium salt of parecoxib is used clinically as an injection. Diacetophenone oxime is an intermediate for the preparation of parecoxib. |
Use | diacetophenone oxime is an organic compound that is an intermediate in the preparation of parecoxib. |