N-(3-fluorobenzyl)propan-2-amine is an organic compound with the formula C11H16FN. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Usually a colorless liquid.
-Solubility: Soluble in many organic solvents such as ethanol, methanol and dichloromethane.
Use:
-Chemical synthesis: N-(3-fluorobenzyl)propan-2-amine is often used as an intermediate in organic synthesis to synthesize other target compounds.
-Drug research: Due to its unique chemical structure, N-(3-fluorobenzyl)propan-2-amine is also used as a research compound in drug research.
Method:
The preparation method of N-(3-fluorobenzyl)propan-2-amine is complicated and usually needs to be carried out in the laboratory. One of its preparation methods is as follows:
1. At low temperature, benzyl chloride (C6H5CH2Cl) and CuF react to produce 3-fluorobenzyl benzyl copper intermediate.
2. Add 2-chloroisopropylamine (C3H7NHCl) to the intermediate solution, and generate N-(3-fluorobenzyl)propan-2-amine through reduction reaction under neutral conditions.
Safety Information:
- N-(3-fluorobenzyl)propan-2-amine is an organic compound. When using, pay attention to fire prevention and avoid contact with skin, eyes and respiratory tract.
-use and storage, should comply with the relevant chemical safety procedures, wear protective gloves and protective glasses.
-When operating in the laboratory, maintain a well-ventilated environment to avoid vapor inhalation or skin contact.
-When using or handling this compound, be sure to follow local safety regulations and conduct proper waste disposal.