865156-68-9 - Names and Identifiers
865156-68-9 - Physico-chemical Properties
Molecular Formula | C6H4BrN3
|
Molar Mass | 198.02 |
Density | 1.89±0.1 g/cm3(Predicted) |
Melting Point | 215-216° |
pKa | 3.80±0.30(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Sensitive | Moisture Sensitive |
865156-68-9 - Risk and Safety
Risk Codes | R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
|
WGK Germany | 3 |
Hazard Class | IRRITANT |
865156-68-9 - Introduction
6-Bromoimidazo[1,2-a]pyrimidine is an organic compound with the chemical formula C6H4BrN3. The following is a description of the nature, use, preparation and safety information of 6-Bromoimidazo[1,2-a]pyrimidine:
Nature:
-Appearance: 6-Bromoimidazo[1,2-a]pyrimidine is a white to pale yellow crystalline solid.
-Melting point: about 182-186°C.
-Solubility: 6-Bromoimidazo[1,2-a]pyrimidine has good solubility in common organic solvents.
Use:
- 6-Bromoimidazo[1,2-a]pyrimidine is an important intermediate compound, widely used in organic synthesis reactions.
-It can be used to synthesize imidazo [1,2-a] pyrimidine analogs for the development of new drugs.
Preparation Method:
The common synthetic methods of 6-Bromoimidazo[1,2-a]pyrimidine are as follows:
1. 5-bromoimidazo [1,2-a] pyrimidine reacts with methyl bromide to give 5,6-dibromoimidazo [1,2-a] pyrimidine.
2. Using the activated metal method, 5,6-dibromoimidazo [1,2-a]pyrimidine reacts with palladium and other metal catalysts to carry out aromatic carbonylation reaction to obtain 6-Bromoimidazo[1,2-a]pyrimidine.
Safety Information:
- 6-Bromoimidazo[1,2-a]pyrimidine should be considered hazardous. Please avoid inhalation, contact with skin or eyes, and ensure that you operate in a well-ventilated place.
-Wear personal protective equipment such as protective gloves, goggles and protective clothing when using or handling the compound.
-If you take it by mistake or have other accidents, please seek medical advice immediately.
-Waste should be disposed of in accordance with local environmental regulations.
Last Update:2024-04-10 22:29:15