828-81-9

828-81-9 - Names and Identifiers

Name	1,3,4-Thiadiazol-2-amine, 5-(2-chlorophenyl)-
Synonyms	VITAS-BB TBB000090 5-(2-Chlorophenyl) IFLAB-BB F1386-0067 5-(2-CHLOROPHENYL)-1,3,4-THIADIAZOL-2-AMINE 2-AMINO-5-(2-CHLOROPHENYL)-1,3,4-THIADIAZOLE 1,3,4-Thiadiazol-2-amine, 5-(2-chlorophenyl)- 1,3,4-Thiadiazol-2-aMine, 5-(2-chlorophenyl)- 5-(2-CHLORO-PHENYL)-[1,3,4]THIADIAZOL-2-YLAMINE
CAS	828-81-9

828-81-9 - Physico-chemical Properties

Molecular Formula	C8H6ClN3S
Molar Mass	211.67
Density	1.461±0.06 g/cm3(Predicted)
Melting Point	192-195 °C
Boling Point	393.8±44.0 °C(Predicted)
pKa	2.28±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

828-81-9 - Risk and Safety

Risk Codes	25 - Toxic if swallowed
Safety Description	45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
Hazard Class	IRRITANT

828-81-9 - Introduction

1,3,4-Thiadiazol-2-amine, 5-(2-chlorophenyl)-is an organic compound with the chemical formula C8H6ClN3S. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: A colorless crystalline solid.
-Melting point: about 100-102 ℃.
-Relative molecular mass: 219.67g/mol.
-Solubility: Soluble in some organic solvents, such as chloroform, dichloromethane, etc.

Use:
- 1,3,4-Thiadiazol-2-amine, 5-(2-chlorophenyl)-has potential application value in the field of pesticides, and may be used as an intermediate for fungicides or herbicides.
-It can also be used as a synthetic intermediate in the pharmaceutical field for the synthesis of biologically active compounds.

Preparation Method:
1,3,4-Thiadiazol-2-amine, 5-(2-chroophenyl)-can be prepared by the following synthetic route:
1. react 5-chloro catechol with thiourea to obtain 5-chloro phthalimide.
2. React with boric acid to obtain the corresponding boric acid ester.
3. Further react with hydrated ammonia to obtain 1,3,4-Thiadiazol-2-amine, 5-(2-chlorophenyl)-.

Safety Information:
- 1,3,4-Thiadiazol-2-amine, 5-(2-chlorine)-Toxicity and hazard data are scarce. But as an organic compound, it can be dangerous.
-During use, appropriate personal protective measures should be taken, such as wearing gloves and glasses, to avoid direct contact with skin and eyes.
-During storage and handling, it is necessary to follow the safe handling procedures for chemicals and avoid contact with substances such as strong oxidants.

Please note that the above information is for reference only. Please ensure that relevant safety procedures are followed when using chemicals and correct chemical laboratory procedures are followed.

Last Update：2024-04-09 15:18:00