785835-79-2
JDTic (dihydrochloride)
CAS: 785835-79-2
Molecular Formula: C28H40ClN3O3
785835-79-2 - Names and Identifiers
785835-79-2 - Physico-chemical Properties
| Molecular Formula | C28H40ClN3O3 |
| Molar Mass | 502.0885 |
| Solubility | 10 mM in DMSO |
| Storage Condition | -20℃ |
| In vivo study | JDTic (2.5-16 mg/kg, s.c.) dose-dependently blocks the antinociceptive response of nicotine in the tail-flick test but has no effect in the hot-plate assay or body temperature assessments at any dose tested in the mice injected with nicotine. JDTic (3 mg/kg, i.p.) is capable of reversing anxiety-like behavior in the rat model of hangover anxiety. JDTic (10 mg/kg, i.p.) decreases alcohol self-administration, suppresses cue-induced reinstatement of alcohol seeking, and specifically blocks the effects of a KOR agonist at the 2 h pretreatment time point. JDTic (30 mg/kg, i.g.) significantly blockes U50,488-induced diuresis immediately in rats. |
785835-79-2 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.857 ml | 9.284 ml | 18.568 ml |
| 5 mM | 0.371 ml | 1.857 ml | 3.714 ml |
| 10 mM | 0.186 ml | 0.928 ml | 1.857 ml |
| 5 mM | 0.037 ml | 0.186 ml | 0.371 ml |
Last Update：2024-01-02 23:10:35
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View History
785835-79-2
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TNS2蛋白
680618-14-8
1783563-56-3
CHF 4226
6342-54-7
(Z,E,E,E)-1-[9-(4-Methoxy-2,3,6-triMethylphenyl)-3,7-diMethyl-2,4,6,8-nonatetraenoate] β-D-Glucopyranuronic Acid
3-bromo-4-tert-butyl-N-(4-chlorophenyl)benzamide
(R)-BENZYL GLYCIDYL ETHER
2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9-Hexadecafluorononyl methacrylate