Name | Caged cGMP |
Synonyms | CGMP cGMP cyclicgmp Caged cGMP 3',5'-CGMP 3',5'-cGMPH Cyclic guanosine phosphate Cyclic 3',5'-guanylic acid Guanosine 3',5'-Monophosphate Guanosine 3',5'-cyclophosphate Guanosine 3',5'-phosphoric acid Guanosine cyclic 3',5'-monophosphate 3',5'-Cyclic guanosine Monophosphate CGMP, GUANOSINE-3',5'-CYCLIC MONOPHOSPHATE GUANOSINE-3',5'-CYCLIC-MONOPHOSPHORIC ACID Guanosine 3′,5′-cyclic monophosphate,cGMP, cyclic GMP 2-amino-9-(2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl)-3,9-dihydro-6H-purin-6-one 2-amino-9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-3,9-dihydro-6H-purin-6-one |
CAS | 7665-99-8 |
EINECS | 231-641-6 |
InChI | InChI=1/C10H12N5O7P/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17)/t3-,5-,6-,9-/m1/s1 |
Molecular Formula | C10H12N5O7P |
Molar Mass | 345.21 |
Density | 2?+-.0.1 g/cm3(Predicted) |
Melting Point | >242°C (dec.) |
Boling Point | 792.7°C at 760 mmHg |
Flash Point | 433.2°C |
Solubility | 1% sodium bicarbonate: 50 mg/mL |
Vapor Presure | 1.71E-26mmHg at 25°C |
Appearance | powder |
Color | white |
pKa | 1.03±0.60(Predicted) |
Storage Condition | -20°C |
Stability | Hygroscopic |
Refractive Index | 2.064 |
Physical and Chemical Properties | Properties: This product is white powder, soluble in water, insoluble in ethanol, under the condition of PH1 A250/A260 = 0.96±0.05; A280/A260 = 0.67±0.03; Λmax = 256±1nm. This product can be used as pharmaceutical and chemical intermediates and biochemical reagents storage conditions − 20°C solubility: 50 mg/mL form powder color white |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
HS Code | 29349990 |
Toxicity | The product formed by the guanylate cyclase enzymes from GTP. It is a cellular “second messenger,” participating in the regulation of many intracellular events. Toxicants (e.g., nitroprusside) may cause physiological changes by interfering with aspects of cyclic GMP metabolism. |
Reference Show more | 1. Shan, Tong, et al. "Proteomics Based Mongolian Medicine Modified Sugmul-7 Mechanism of Regulating Endocrine Function in Hyperplasia of the Breast." Clinical Medicine Research 9.1 (2020): 11.doi: 10.11648/j.cmr.20200901.13 2. [IF=2.629] Wang Ting et al."Network Pharmacology Prediction and Pharmacological Verification Mechanism of Yeju Jiangya Decoction on Hypertension."Evid-Based Compl Alt. 2021;2021:5579129 |