73346-74-4 - Names and Identifiers
Name | (-)-2,3-O-Isopropylidene-D-threitol
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Synonyms | 2,3-O-ISOPROPYLIDENE-D-THREITOL 2,3-DI-O-ISOPROPYLIDENE-D-THREITOL (-)-2,3-O-ISOPROPYLIDINE-D-THREITOL (+)-2,3-O-ISOPROPYLIDINE-D-THREITOL (-)-2,3-O-Isopropylidene-D-threitol (-)-2,3-O-ISOPROPYLIDENE-D-THREITOL D(-)-2,2-DIMETHYL-1,3-DIOXOLANE-4,5-DIMETHANOL D-(-)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol [(4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]dimethanol (4S,5R)-(-)-4,5-BIS(HYDROXYMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE (4R-TRANS) 1,3-DIOXOLANE-4,5-DIMETHANOL-2,2-DIMETHYL BUTANOIC ACID
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CAS | 73346-74-4
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EINECS | 277-391-1 |
InChI | InChI=1/C7H14O4/c1-7(2)10-5(3-8)6(4-9)11-7/h5-6,8-9H,3-4H2,1-2H3/t5-,6-/m1/s1 |
73346-74-4 - Physico-chemical Properties
Molecular Formula | C7H14O4
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Molar Mass | 162.18 |
Density | 1.0585 (rough estimate) |
Melting Point | 48-51°C(lit.) |
Boling Point | 91-93°C0.01mm Hg(lit.) |
Specific Rotation(α) | -3.1 º (c=5, CHCl3 26 ºC) |
Flash Point | >230°F |
Water Solubility | Soluble in water. |
Solubility | Chloroform, Dichloromethane, Ethyl Acetate, THF |
Vapor Presure | 8.03E-06mmHg at 25°C |
Appearance | Oil |
Color | Yellow |
BRN | 1798 |
pKa | 13.90±0.10(Predicted) |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
Sensitive | Hygroscopic |
Refractive Index | -4 ° (C=5, Acetone) |
MDL | MFCD00009761 |
73346-74-4 - Risk and Safety
Hazard Symbols | Xn - Harmful
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Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
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WGK Germany | 3 |
FLUKA BRAND F CODES | 3-10 |
HS Code | 29329970 |
73346-74-4 - Introduction
(-)-2, is an organic compound with a chemical formula of C7H14O4 and a molecular weight of 162.18. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
(-)-2, is a colorless to yellowish solid. It has a unique structure, including a threitol ring in which one of the hydroxyl groups is replaced by an isopropylidene group. The compound is soluble in many organic solvents such as diethyl ether, methanol and ethanol.
Use:
(-)-2, which is often used as a chiral inducer or intermediate in organic synthesis. It can be used in the synthesis of chiral compounds such as pharmaceuticals, natural products and pesticides. The compounds can also be used as ligands or catalysts in organic synthesis reactions.
Preparation Method:
(-)-2, is usually prepared by the following steps: First, D-glycol is subjected to the reaction of stripping the protecting group (such as tyrosol diacetone ketone (CH3CO 2C(OH)Ar) to form 2,3-O-Isopropylidene glycol. Then, by hydrolyzing the tyrosol diacetonone protecting group under acidic conditions, (-)-2, -4 is obtained.
Safety Information:
Regarding (-)-2, the safety research is limited, so use caution when using it. In accordance with general laboratory safety practices, it is necessary to follow protective measures. Direct contact with skin and eyes should be avoided and it should be ensured that the operation is carried out in a well-ventilated place. During use and storage, keep away from heat and fire sources to prevent fire or explosion. Refer to the Safety Data Sheet (MSDS) for chemicals for specific handling and handling.
Last Update:2024-04-09 21:54:55