7-Fluoro-6-methoxy-4-oxo-1,4-dihydro-3-quinolinecarbonitrile - Names and Identifiers
Name | 7-fluoro-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile
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Synonyms | 7-FLUORO-1,4-DIHYDRO-6-METHOXY-4-OXO-3-QUINOLINE 7-fluoro-6-methoxy-4-oxo-1H-quinoline-3-carbonitrile 7-Fluor-6-methoxy-4-oxo-1,4-dihydrochinolin-3-carbonitril 7-fluoro-1,4-dihydro-6-methoxy-4-oxo-3-Quinolinecarbonitrile 7-FLUORO-6-METHOXY-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBONITRILE 7-Fluoro-6-methoxy-4-oxo-1,4-dihydro-3-quinolinecarbonitrile 7-fluoro-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile 7-Fluoro-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile 3-Quinolinecarbonitrile, 7-fluoro-1,4-dihydro-6-Methoxy-4-oxo-
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CAS | 622369-38-4
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InChI | InChI=1/C11H7FN2O2/c1-16-10-2-7-9(3-8(10)12)14-5-6(4-13)11(7)15/h2-3,5H,1H3,(H,14,15) |
7-Fluoro-6-methoxy-4-oxo-1,4-dihydro-3-quinolinecarbonitrile - Physico-chemical Properties
Molecular Formula | C11H7FN2O2
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Molar Mass | 218.18 |
Density | 1.40 |
Boling Point | 362.7±42.0 °C(Predicted) |
Flash Point | 173.157°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 2.26±0.50(Predicted) |
Refractive Index | 1.599 |
7-Fluoro-6-methoxy-4-oxo-1,4-dihydro-3-quinolinecarbonitrile - Introduction
7-fluoro-6-methoxy-4-oxo-1, is an organic compound whose chemical formula is C12H8FN2O2. The following are some information about the properties, uses, preparation and safety of the compound:
Nature:
-Appearance: Colorless or light yellow solid
-Melting point: about 220-222°C
-Solubility: Soluble in common organic solvents such as ethanol, dimethyl sulfoxide and dichloromethane
Use:
- 7-fluoro-6-methoxy-4-oxo-1, which can be used as an intermediate in organic synthesis.
-It is often used in the field of medicinal chemistry to synthesize biologically active compounds, such as anti-tumor drugs and antibacterial drugs.
Preparation Method:
- 7-fluoro-6-methoxy-4-oxo-1, the preparation methods of the process are more diverse, the following is one of the typical preparation methods:
Using 6-methoxy-2-chloro-4-oxoquinoline as the starting material, fluorine atoms are introduced through fluorination reaction, and then 7-fluoro-6-methoxy-2-oxoquinoline-4-carbonitrile is obtained through dechlorination reaction, and finally the target product is obtained through hydrogenation reduction reaction.
Safety Information:
- 7-fluoro-6-methoxy-4-oxo-1, Information on safety is limited.
-This compound may be irritating to the eyes, skin and respiratory system, so care should be taken to avoid contact during operation.
-During use and storage, follow appropriate laboratory safety practices, such as wearing protective gloves and eye protection.
-If necessary, please refer to the safety data sheet and operation manual provided by the chemical supplier to ensure the correct and safe handling of the compound.
Last Update:2024-04-09 20:49:11